《中国康复理论与实践》

《中国康复理论与实践》 ›› 2011, Vol. 17 ›› Issue (1): 42-44.

• 论文 • 上一篇    下一篇

帕金森病运动前期研究进展

焦淑军1,袁红2综述,梁立武2审校   

  1. 1.辽宁医学院中西医结合临床, 辽宁锦州市 121001;2.武警总医院神经内科，北京市 100039。
  • 收稿日期:2010-12-07 修回日期:1900-01-01 出版日期:2011-01-25 发布日期:2011-01-25
  • 通讯作者: 梁立武

Premotor Phase of Early Parkinson Disease (review)

JIAO Shu-jun, YUAN Hong, LIANG Li-wu.   

  1. Integrated Traditional Chinese & Western Medicine, Liaoning Medicine University, Jinzhou 121001, Liaoning, China
  • Received:2010-12-07 Revised:1900-01-01 Published:2011-01-25 Online:2011-01-25

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被引次数

3

摘要： 临床症状学及神经影像学、病理学的资料均提示各种帕金森病（PD）非运动症状（NMS），如嗅觉障碍、自主神经机能异常、情感障碍、睡眠紊乱等，先于运动症状出现数年至十数年，这段时期称为运动前期（premotor phase）。本文对帕金森病运动前期概念、临床表现、病理基础、诊断的研究进展做一综述。

关键词: 帕金森病, 运动前期, 非运动症状, 综述

Abstract: Clinical, neuroimaging, and pathologic studies suggested that a variety of nonmotor symptoms, such as olfactory dysfunction, dysautonomia, and mood and sleep disorders, can precede the typic motor features of Parkinson disease (PD) by years and, perhaps, even decades. The period when these symptoms arise can be referred as the premotor phase of the disease. This paper reviewed the conception, clinical manifestation, pathology, diogose of the premotor phase of early Parkinson disease.

Key words: Parkinson disease, premotor phase, nonmotor symptoms, review