《中国康复理论与实践》

《中国康复理论与实践》 ›› 2012, Vol. 18 ›› Issue (3): 256-258.

• 论文 • 上一篇    下一篇

扩充痴呆量表对慢性阻塞性肺疾病认知功能的评价

赵松林1a，聂秀红1a，张威1a，魏兵1a，任魁1a，冀瑞俊1b   

  1. 1.首都医科大学宣武医院，a.呼吸内科；b.神经内科，北京市 100053。
  • 收稿日期:2011-07-12 修回日期:1900-01-01 出版日期:2012-03-25 发布日期:2012-03-25

Extended Scale for Dementia on Cognitive Function of Patients with Chronic Obstructive Pulmonary Disease

ZHAO Song-lin, NIE Xiu-hong, ZHANG Wei, et al.   

  1. Department of Respiratory Medicine, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
  • Received:2011-07-12 Revised:1900-01-01 Published:2012-03-25 Online:2012-03-25

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摘要： 目的探讨扩充痴呆量表(ESD)对稳定期慢性阻塞性肺疾病(COPD)患者认知功能的评价作用。方法稳定期COPD患者37 例(COPD 组)根据动脉血氧分压(PaO2)分组；同期北京市城区健康居民40 名为对照组。两组均采用ESD 及简易智能精神状态检查量表(MMSE)进行评定。结果COPD 组ESD 总分及学习、记忆、计算、结构4 项分测验评分均显著低于对照组(P<0.001)。COPD 组MMSE 总分及注意力和计算力、回忆能力、记忆力3 项分测验评分均低于对照组(P<0.05)。PaO2<60 mmHg COPD 患者ESD总分及学习、记忆力和计算力3 项分测验评分均低于PaO2≥60 mmHg COPD患者(P<0.05)，MMSE 总分及注意力和计算力、回忆能力、记忆力3 项分测验评分也低(P<0.05)。ESD总分、MMSE 总分与PaO2均明显相关(P<0.01)。结论ESD可以作为评价稳定期COPD患者认知功能的工具。

关键词: 慢性阻塞性肺疾病, 认知功能, 扩充痴呆量表, 简易智能精神状态检查量表

Abstract: Objective To evaluate the cognitive function of chronic obstructive pulmonary disease (COPD) stable patients with ExtendedScale for Dementia (ESD). Methods 37 patients with stable COPD (COPD group) and 40 healthy persons (control group) were enrolled.The COPD patients were divided into different groups as their PaO2. They were assessed with ESD and Mini Mental Status Examination(MMSE). Results The total score of ESD and the subtest scores of ESD in leaning, memory, calculation, constructive function were significantlylower in the COPD group than in the control group (P<0.001). The total score of MMSE and the subtest scores of MMSE in memory,attention and calculation, short- and long-term memory were significantly lower in the COPD group than in the control group (P<0.05). Thetotal score and the subtest scores in learning, memory, calculation of ESD were lower in patients with PaO2<60 mmHg than those withPaO2≥60 mmHg (P<0.05), same as the total score and the subtest scores in memory, attention and calculation, short- and long-term memoryof MMSE (P<0.05). Both ESD and MMSE correlated significantly with PaO2 (P<0.01). Conclusion ESD can be used as an evaluationtool for cognitive function in stable patients with chronic obstructive pulmonary disease.

Key words: chronic obstructive pulmonary disease, cognitive function, Extended Scale for Dementia, Mini Mental Status Examination