《中国康复理论与实践》

《中国康复理论与实践》 ›› 2012, Vol. 18 ›› Issue (6): 586-587.

• 论文 • 上一篇    下一篇

穴位注射神经生长因子治疗Ramsay Hunt 综合征临床观察

黄彬   

  1. 解放军总医院针灸科，北京市100853。
  • 收稿日期:2011-05-20 修回日期:2012-01-06 出版日期:2012-06-25 发布日期:2012-06-25

Effect of Acupoint Injection with Nerve Growth Factor on Ramsay Hunt Syndrome

HUANG Bin.   

  1. Department of Acupuncture and Moxibustion, General Hospital of PLA, Beijing 100853, China
  • Received:2011-05-20 Revised:2012-01-06 Published:2012-06-25 Online:2012-06-25

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被引次数

6

摘要： 目的观察电针结合穴位注射鼠神经生长因子治疗Ramsay Hunt 综合征的临床疗效及后遗神经痛发生率。方法65 例患者按就诊单双日分为试验组(n=33)和对照组(n=32)，两组患者就诊时给予抗病毒及糖皮质激素治疗，并即时电针治疗，电针取穴采用阳白-旁阳白(阳白外侧1.5 寸)、承泣-瞳子髎、颊车-牵正、颧髎-地仓、迎香-上迎香5 组；试验组在此基础上加用穴位注射鼠神经生长因子，穴位注射取穴完骨、阳白、颧髎、地仓。每治疗5 次休息2 d，10 次为1 个疗程，治疗2 个疗程后，比较治疗效果和3个月后神经痛发生率。结果试验组总有效率(93.9%)明显高于对照组(71.9%)(P<0.01)。3 个月后随访62 例，丢失3 例，随访率为95.4%。试验组后遗神经痛发生率(6.3%)明显低于对照组(26.7%)(P<0.01)。结论电针结合穴位注射鼠神经生长因子治疗RamsayHunt 综合征可提高疗效，降低后遗神经痛发生率。

关键词: Ramsay Hunt 综合征, 电针疗法, 穴位注射, 神经生长因子, 神经痛

Abstract: Objective To observe the clinical effect and the incidence of neuralgia of acupoint injection with nerve growth factor onRamsay Hunt syndrome. Methods 65 patients with Ramsay Hunt syndrome were divided into treatment group (n=33) and control group(n=32). All the patients were treated with the anti-virus and glucocorticoid medicine, and were acupunctured at the similar points with electroacupuncturewith the disperse dense wave. The treatment group was injected with mouse nerve growth factor at the acupoints. 2 days offevery 5 times, 10 times as a course for 2 courses. The treatment effect and the incidence of sequelae neuralgia after 3 months were compared.Results The total effective rate of treatment group (93.9%) was significantly higher than control group (71.9%) (P<0.01). The incidenceof sequelae neuralgia of the treatment group (6.3%) was significantly lower than the control group (26.7%) (P<0.01). ConclusionAcupoint injection of mouse nerve growth factor can improve the efficacy and reduce the incidence rate of sequelae neuralgia in patientswith Ramsay Hunt syndrome.

Key words: Ramsay Hunt syndrome, electroacupuncture therapy, acupoint injection, nerve growth factor, neuralgia