《中国康复理论与实践》

《中国康复理论与实践》 ›› 2012, Vol. 18 ›› Issue (7): 634-635.

• 论文 • 上一篇    下一篇

电项针对急性脑梗死患者脑脊液及血液5-羟色胺的影响

李宝栋，白晶，杨迎国，王志勇   

  1. 河北医科大学附属沧州中西医结合临床医学院神经内科，河北沧州市061001。
  • 收稿日期:2011-12-13 修回日期:2012-04-13 出版日期:2012-07-25 发布日期:2012-07-25
  • 通讯作者: 白晶

Effect of Nucha Electroacupuncture on 5-hydroxytryptamine in Cerebrospinal Fluid and Blood of Acute Cerebral Infarction Patients

LI Bao-dong, BAI Jing, YANG Ying-guo, et al   

  1. Department of Neurology, Cangzhou Hospital of Integrated Chinese and Western Medicine, Cangzhou 061001, Hebei, China
  • Received:2011-12-13 Revised:2012-04-13 Published:2012-07-25 Online:2012-07-25

PDF (PC)

摘要：

目的研究电项针对急性脑梗死患者脑脊液及血液中5-羟色胺(5-HT)的影响。方法72 例首发急性脑梗死患者随机分为电项针组(38 例)和对照组(34 例)，分别于治疗前和治疗4 周后测定脑脊液和血液中5-HT 浓度。结果治疗前，脑脊液5-HT：电项针组(0.67±0.13) μmol/L，对照组(0.71±0.11) μmol/L (P>0.05)；血液中5-HT：电项针组(0.44±0.19) μmol/L，对照组(0.41±0.10)μmol/L(P>0.05)；治疗后，脑脊液5-HT：电项针组(1.12±0.32) μmol/L，对照组(0.83±0.15) μmol/L (P<0.05)；血液中5-HT：电项针组(0.87±0.13) μmol/L，对照组(0.63±0.07) μmol/L (P<0.05)。结论电项针早期干预能够增加急性脑梗死患者脑脊液及血液中5-HT浓度，可能有益于卒中后抑郁的早期干预。

关键词: 急性脑梗死, 卒中后抑郁, 电项针, 5-羟色胺

Abstract: Objective To study the effect of nucha electroacupuncture (NEA) on 5-hydroxytryptamine (5-HT) in cerebrospinal fluid (CSF) and blood of acute cerebral infarction (ACI) patients. Methods 72 cases with first ACI were randomly divided into NEA group (n= 38) and control group (n=34). Their 5-HT levels in CSF and blood were determined before and 4 weeks after treatment. Results Before treatment, the 5-HT in the CSF was (0.67±0.13) μmol/L in the NEA group and (0.71±0.11) μmol/L in the control group (P>0.05), while that in the blood was (0.44±0.19) μmol/L in the NEA group and (0.41±0.10) μmol/L in the control group (P>0.05). After treatment, the 5-HT in the CSF was (1.12±0.32) μmol/L in the NEA group and (0.83±0.15) μmol/L in the control group (P<0.05), while that in the blood was (0.87± 0.14) μmol/L in the NEA group and (0.63±0.07) μmol/L in the control group (P<0.05). Conclusion NEA can increase the 5-HT in both CSF and blood after ACI, which may facilitate to reduce post-stroke depression.

Key words: acute cerebral infarction, post-stroke depression, nucha electrical acupuncture, 5-hydroxytryptamine