《中国康复理论与实践》

《中国康复理论与实践》 ›› 2012, Vol. 18 ›› Issue (9): 837-839.

• 论文 • 上一篇    下一篇

中文版阿尔茨海默病联合注册表-神经心理学成套测试的测试者间信度与受试者工作特征

张雪艳1,2，周裕婧1,3，廖佩仪1,4   

  1. 1.香港理工大学康复治疗系，香港九龙；2.北京市丰台区铁营医院，北京市100078；3.重庆医药高等专科学校，重庆市401331；4.西悉尼大学，澳大利亚悉尼。
  • 收稿日期:2012-03-04 修回日期:2012-07-27 出版日期:2012-09-25 发布日期:2012-09-25
  • 通讯作者: 廖佩仪

Inter-rater Reliability and Receiver Operating Characteristic of Chinese Consortium to Establish a Registry for Alzheimer's Disease: Neuropsychological Assessment Battery

ZHANG Xue-yan, ZHOU Yu-jing, LIU Karen P.Y.   

  1. Hongkong Polytechnic Univeristy, Hongkong,China
  • Received:2012-03-04 Revised:2012-07-27 Published:2012-09-25 Online:2012-09-25

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摘要： 目的评价中文版阿尔茨海默病联合注册表-神经心理学成套测试(CERAD-NAB)判别轻度认知障碍(MCI)的测试者间信度和效度。方法52 例60 岁以上老年人采用中文版CERAD-NAB 进行测评，根据Petersen 等制定的标准确定MCI 诊断。计算不同测试者间组内相关系数(ICC)；绘制受试者工作特征(ROC)曲线，计算曲线下面积(AUC)。结果CERAD-NAB 各子测试ICC=0.945~1。CERAD-NAB 总分AUC 为0.747，在界值为62.5 时，敏感性和特异性分别为0.52 和0.90；CERAD-NAB 总分和子测试J3、J8 AUC较高。结论中文版CERAD-NAB测试者间信度很高，在判别MCI 方面效度满意。

关键词: 阿尔茨海默病联合注册表-神经心理学成套测试, 信度, 效度, 轻度认知障碍

Abstract: Objective To evaluate the inter-rater reliability and validity of Chinese version Consortium to Establish a Registry for Alzheimer's Disease: Neuropsychological Assessment Battery (CERAD-NAB) in discriminating mild cognitive impairment (MCI). Methods 52 old people (31 normal elderly, 21 MCI, according to the Petersen's criterion) were assessed with CERAD-NAB-C. The intra-class correlation coefficient (ICC), receiver operating characteristic (ROC) curve, and area under the curve (AUC) were analyzed. Results The ICC was 0.945~1 in subtests of CERAD-NAB. The AUC was 0.747, the sensitivity and specificity of total score was 0.52 and 0.90 respectively at a cut-off score of 62.5. J3, J8, and total score had higher AUC than other subtests in discriminating MCI from normals. Conclusion The inter- rater reliability of CERAD-NAB was perfect, and the validity was satisfactory in discriminating MCI from normals

Key words: Consortium to Establish a Registry for Alzheimer's Disease: Neuropsychological Assessment Battery, reliability, validity, mild cognitive impairment