《中国康复理论与实践》

《中国康复理论与实践》 ›› 2013, Vol. 19 ›› Issue (06): 501-504.

• 论文 •    下一篇

膝关节创伤后炎性细胞因子变化的研究现状

王飞，刘克敏   

  1. 1.首都医科大学康复医学院，北京市100068；2.中国康复研究中心北京博爱医院骨科，北京市100068。
  • 收稿日期:2013-05-31 修回日期:1900-01-01 出版日期:2013-06-25 发布日期:2013-06-25
  • 通讯作者: 刘克敏

Advance in Inflammatory Cytokines in Post-traumatic Knee (review)

WANG Fei, LIU Ke-min.   

  1. Capital Medical University School of Rehabilitation Medicine,Department of Orthopedic Surgery, Beijing Bo'ai Hospital, China Rehabilitation Research Center, Beijing 100068,China
  • Received:2013-05-31 Revised:1900-01-01 Published:2013-06-25 Online:2013-06-25

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摘要： 膝关节创伤后周围组织，包括关节囊、滑膜、关节软骨、半月板等，均能产生炎症介质，这就提示膝关节创伤后疼痛及僵直与其局部的炎症反应及炎性细胞因子有关。这些炎性细胞因子中有促进和加速炎症反应的因子如肿瘤坏死因子、白细胞介素-1、白细胞介素-2、白细胞介素-6、环氧酶等。本文介绍膝关节创伤后周围组织部分炎性细胞因子的研究现状，分析目前研究存在的不足，为进一步研究奠定基础。

关键词: 创伤后膝关节, 炎性细胞因子, 肌肉细胞, 综述

Abstract: Tissues around the post-traumatic knee, including the capsule, synovial, articular cartilage, meniscus, etc., can produce inflammatory mediators. This suggested that post-traumatic knee pain and stiffness are related with local inflammation and inflammatory cytokines.These inflammatory cytokines included the inflammatory response factor of advancement and acceleration, such as tumor necrosis factor, interleukin-1, interleukin-2, interleukin-6, cyclooxygenase, etc. This article reviewed the researches about some inflammatory cytokines surrounding tissue of post-traumatic knee, analyzed current research shortcomings, and established the foundation for further study.

Key words: post-traumatic knee, inflammatory cytokines, muscle cells, review