《中国康复理论与实践》

《中国康复理论与实践》 ›› 2014, Vol. 20 ›› Issue (11): 1004-1007.

• 专题 • 上一篇    下一篇

健康人双任务范式汉字加工的功能磁共振成像研究

裴倩，宋鲁平，张通   

  1. 1.北京积水潭医院康复医学科，北京市100035；2.中国康复研究中心北京博爱医院神经康复科，北京市100068；3.首都医科大学康复医学院，北京市100068。
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2014-11-25 发布日期:2014-11-25

Chinese Characters Processing of Healthy Subjects: A Functional Magnetic Resonnce Imaging Study

PEI Qian, SONG Lu- ping,ZHANG Tong   

  1. Department of Rehabilitation, Beijing Jishuitan Hospital, Beijing 100035, China
  • Received:1900-01-01 Revised:1900-01-01 Published:2014-11-25 Online:2014-11-25

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被引次数

5

摘要： 目的利用功能磁共振成像(fMRI)考察健康人双任务范式下汉字加工过程。方法10 名健康受试者分别进行双任务范式的“ 按键朗读” 任务及单任务范式的“ 按键”“ 朗读” 任务。采用标准的组块相关设计对受试者大脑进行fMRI扫描，观察任务中脑功能激活区及偏侧化指数。结果和结论执行任务时，右侧额下回、双侧顶叶、双侧小脑显著激活；偏侧化指数显示，脑激活区呈现左半球优势。

关键词: 汉字加工, 功能磁共振成像, 脑功能激活区, 偏侧化指数

Abstract: Objective To investigate the Chinese characters processing in healthy subjects with functional magnetic resonance imaging (fMRI). Methods 10 healthy subjects were asked to finish the dual-task paradigm Keying/Reading and single-task paradign Keying or Reading.The active area and partial lateralization index in brains of them were investigated with fMRI with block design. Results and onclusion The tasks activated the right inferior frontal gyrus, bilateral parietal and cerebellar cortex. The laterality index showed that the left brains were more active in the tasks.

Key words: Chinese characters processing, functional magnetic resonance imaging, active area, partial lateralization index