《中国康复理论与实践》

《中国康复理论与实践》 ›› 2014, Vol. 20 ›› Issue (6): 576-579.

• 论文 • 上一篇    下一篇

慢性疲劳综合征与抑郁症、焦虑症患者临床症状的差异

陈敏1，张振贤1，周展红1，王晓静2，张烨1，吴丽丽1   

  1. 1.上海中医药大学附属岳阳医院中医内科，上海市200433；2.上海中医药大学，上海市201203
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2014-06-25 发布日期:2014-06-25

Differences of Clinical Symptoms among Chronic Fatigue Syndrome, Depression or Anxiety

CHEN Min, ZHANG Zhen-xian, ZHOU Zhan-hong, et al.   

  1. Yueyang Hospital Affiliated to Shanghai University of Chinese Medicine, Shanghai 200433, China
  • Received:1900-01-01 Revised:1900-01-01 Published:2014-06-25 Online:2014-06-25

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摘要： 目的分析研究慢性疲劳综合征(CFS)与轻中度抑郁症、焦虑症患者疲劳特征及抑郁、焦虑症状的差异。方法运用疲劳量表-14(FS-14)、汉密尔顿抑郁量表(HAMD)和汉密尔顿焦虑量表(HAMA)对182 例CFS及轻中度抑郁症、焦虑症患者进行测评及统计分析。结果三组患者在躯体疲劳程度、精神疲劳程度及疲劳总分各方面均无显著性差异(P>0.05)；CFS组患者可能有抑郁症状的患者为39 例(62.9%)，伴有轻中度抑郁症状的患者为23 例(37.1%)，未发现肯定没有抑郁症状的患者；CFS组患者可能有焦虑症状的46 例(74.2%)，肯定有焦虑症状的16 例(25.8%)，未发现肯定没有焦虑症状的患者；CFS组HAMD总分显著低于轻中度抑郁症组(P<0.001)，两组在焦虑/躯体化、阻滞两因子中有非常显著性差异(P<0.01)，在认识障碍、日夜变化、绝望感各因子中有显著性差异(P<0.05)。CFS组HAMA总分显著低于轻中度焦虑症组(P<0.001)，两组在精神性焦虑方面有非常显著性差异(P<0.01)，在躯体性焦虑各方有显著性差异(P<0.05)。结论CFS与轻中度抑郁症、焦虑症三组患者在临床中均表现为“郁”与“疲”的同时存在，在临床症状的表现上存在着一定的“相互重叠”现象。

关键词: 慢性疲劳综合征, 抑郁症, 焦虑症, 疲劳

Abstract: Objective To observe the difference among the patients with chronic fatigue syndrome (CFS), mild-to-moderate depression or anxiety disorders in symptoms of fatigue, depression and anxiety. Methods Fatigue Scale-14 (FS-14), Hamilton Rating Scale for Depression (HAMD) and Hamilton Rating Scale for Anxiety (HAMA) were used to evaluate 182 cases with CFS, mild-to-moderate depression or anxiety disorders. Results There was no significant difference in physical fatigue, mental fatigue and comprehensive fatigue among 3 groups (P>0.05). There were 39 (62.9%) CFS patients perhaps with depression symptoms and 23 (37.1%) patients with mild-to-moderate depression symptoms. There were 46 (74.2%) CFS patients perhaps with anxiety symptoms and 16 (25.8%) patients with mild-to-moderate anxiety symptoms. The score of HAMD was significant lower in the CFS group than in the mild-to-moderate depression disorder group (P<0.001). There were significant differences in the anxiety/somatization and hysteresis (P<0.01), as well as in cognitive disturbance, diurnal variation and hopelessness (P<0.05) between the CFS group and mild-to-moderate depression disorder group. The scores of HAMA was significant lower in the CFS group than in the mild-to- moderate anxiety disorder group (P<0.001). There was significant difference in mental-anxiety (P<0.01), as well as in body-anxiety (P<0.05) between the CFS group and the mild-to-moderate anxiety disorder group. Conclusion The symptoms of emotion disorders and fatigue symptoms were both presented in patients with CFS, mild-to-moderate depression and
anxiety disorders. They share common clinical features.

Key words: chronic fatigue syndrome, depression, anxiety, fatigue