《中国康复理论与实践》

《中国康复理论与实践》

• 临床观察 • 上一篇    下一篇

脑卒中后皮质脊髓束与上肢运动功能关系的弥散张量成像研究①

张丽华1a，郭龙军1b，郄淑燕1a，米立新1a，王璐怡1a，甄巧霞1a   

  1. 1.首都医科大学附属北京康复医院，a.康复诊疗中心；b.放射科，北京市100144。
  • 出版日期:2016-01-25 发布日期:2016-05-23

Relationship between Corticospinal Cord Tract and Upper Limb Function in Stroke Patient: A Diffusion Tensor Imaging Study

ZHANG Li-hua1a, GUO Long-jun1b, QIE Shu-yan1a, MI Li-xin1a, WANG Lu-yi1a, ZHEN Qiao-xia1a   

  1. 1. a. Rehabilitaiton Department; b. Radiology Department, Beijing Rehabilitation Hospital, Capital Medical University, Beijing 100144, China
  • Published:2016-01-25 Online:2016-05-23

PDF (PC)

摘要： 目的应用弥散张量成像(DTI)观察脑卒中患者基底节区皮质脊髓束损伤情况及其与上肢运动功能的关系。方法2013 年1 月~2015 年7 月住院脑卒中患者18 例接受DTI，并采用简式Fugl-Meyer 评定和金子翼上肢功能评定进行评分，比较病灶侧与健侧基底节区皮质脊髓束部分各向异性(FA)，对病灶侧FA与上肢运动功能评分进行相关性分析。结果患侧FA显著小于健侧(t=-21.09, P<0.001)。患侧FA与Fugl-Meyer 评分正相关(r=0.570, P<0.05)，与金子翼上肢功能评分正相关(r=0.509, P<0.05)。结论脑卒中后基底节区皮质脊髓束受损，损伤程度与上肢运动功能相关。

关键词: 脑卒中, 弥散张量成像, 皮质脊髓束, 上肢, 运动功能

Abstract: Objective To observe the relationship between injury of corticospinal cord tract (CST) in basal ganglia and upper limb function after stroke using diffusion tensor imaging (DTI). Methods 18 stroke inpatients hospitalized from January, 2013 to July, 2015 accepted DTI, and their upper limb function was evaluated with simple Fugl-Meyer Assessment and Japan Upper Limb Function Test. The fractional anisotropy (FA) of CST in basal ganglia of affected and unaffected sides were compared, and the correlation between FA of affected CST and upper limb motor function were analyzed. Results The FA was significantly less in the affected CST than in the unaffected CST (t=-21.09, P<0.001). The FA of the affected CST correlated with the scores of simple Fugl-Meyer Assessment (r=0.570, P<0.05) and Japan Upper Limb Function Test (r=0.509, P<0.05). Conclusion CST is injured after stroke, which may related to the upper limbs motor function impairment.

Key words: stroke, diffusion tensor imaging, corticospinal cord tract, upper limbs, motor function