《中国康复理论与实践》

《中国康复理论与实践》

• 临床研究 • 上一篇    下一篇

重复经颅磁刺激对脑性瘫痪并发癫痫患儿运动功能的影响①

王迎红，周正   

  1. 河南中医学院第一附属医院儿科三病区，河南郑州市450000。
  • 出版日期:2016-01-25 发布日期:2016-05-23

Effect of Repetitive Transcranial Magnetic Stimulation on Motor Function in Cerebral Palsy Children with Epilepsy

WANG Ying-hong, ZHOU Zheng   

  1. Department of Pediatrics, The First Affiliated Hospital of Henan College of Traditional Chinese Medicine, Zhengzhou, Henan 450000, China
  • Published:2016-01-25 Online:2016-05-23

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摘要： 目的探讨重复经颅磁刺激(rTMS)对脑瘫并发癫痫患儿运动功能的影响。方法2011 年2 月~2014 年9 月本院就诊的脑瘫并发癫痫患儿270 例，随机数字表法分为对照组(n=130)和治疗组(n=140)。对照组采用综合康复治疗，包括推拿按摩、运动疗法、作业疗法、物理因子疗法、言语疗法、认知知觉功能训练及药物治疗；治疗组在对照组基础上加用rTMS。治疗前，治疗1 个月、2 个月，采用88 项粗大运动功能测量量表(GMFM-88)和Peabody 发育量表粗大运动部分(PDMS-GM)进行评定。结果治疗后，治疗组GMFM-88 和PDMS-GM总标准分均较对照组显著提高(F>93.9, P<0.001)。结论rTMS能进一步提高脑瘫并发癫痫患儿的运动功能。

关键词: 脑性瘫痪, 癫痫, 重复经颅磁刺激, 粗大运动功能, 发育

Abstract: Objective To explore the effect of repetitive transcranial magnetic stimulation (rTMS) on motor function in cerebral palsy children with epilepsy. Methods 270 cerebral palsy children with epilepsy hospitalized from February, 2011 to September, 2014 were randomized to control group (n=130) and treatment group (n=140). The control group received comprehensive rehabilitation, including massage, exercise, occupational therapy, physiotherapy, speech training, cognitive function training and medication, and the treatment group received rTMS in addition. They were assessed with Gross Motor Function Measure-88 (GMFM-88) and Peabody Developmental Measure Scale-Gross Motor (PDMS-GM) before, and 1 and 2 months after treatment. Results The total scores of GMFM-88 and PDMS-GM increased more in the treatment group than in the control group (F>93.9, P<0.001). Conclusion rTMS can further improve the motor function in cerebral palsy children with epilepsy.

Key words: cerebral palsy, epilepsy, repetitive transcranial magnetic stimulation, gross motor function, development