《中国康复理论与实践》

《中国康复理论与实践》

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外周神经电刺激引导下A型肉毒毒素注射治疗面肌痉挛57 例观察①

邵银进，黄裕斌，吴桂华   

  1. 赣州市人民医院康复医学科，江西赣州市341000。
  • 出版日期:2016-03-25 发布日期:2016-06-01

Effect of Botulinum Toxin A Injection Guided by Peripheral Nerve Stimulation on Hemifacial Spasm: 57 Cases Report

SHAO Yin-jin, HUANG Yu-bin, WU Gui-hua   

  1. Department of Rehabilitation Medicine, Ganzhou People's Hospital, Ganzhou, Jiangxi 341000, China
  • Published:2016-03-25 Online:2016-06-01

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摘要： 目的探讨在外周神经电刺激引导下A型肉毒毒素(BTX-A)局部注射治疗面肌痉挛的疗效。方法2012 年1 月~2015年6 月，57 例面肌痉挛患者在外周神经电刺激引导下采用BTX-A局部多点注射。治疗前、治疗后72 h 和6 个月，进行面肌痉挛强度评级，根据面肌痉挛强度评级进行疗效评定。随访3~9 个月。结果患者治疗后面肌痉挛强度均较治疗前改善。治疗72 h 后有效率为98.25%，治疗6 个月后有效率为91.23% (χ2=4.946, P<0.05)；疗效平均维持(23.1±2.3)周。结论外周神经电刺激引导下BTX-A局部多点注射治疗面肌痉挛疗效显著且持久。

关键词: 面肌痉挛, A型肉毒毒素, 外周神经电刺激

Abstract: Objective To investigate the effects of local injection of Botulinum toxin A (BTX-A) on hemifacial spasm guided by peripheral nerve stimulation. Methods 57 patients with hemifacial spasm from January, 2012 to June, 2015 received local multi-point injection of BTX-A guided by peripheral nerve stimulation. The grades of facial spasm were evaluated before, 72 hours and 6 months after treatment. They were followed up for 3-9 months. Results The spasm reduced in the patients both 72 hours and 6 months after treatment (χ2=4.946, P< 0.05). The incidence was 98.25% of satisfaction and 92.99% of very well 72 hours after treatment, while it was 91.23% and 78.95% 6 months after treatment. The relief of spasm was maintained for (23.1±2.3) weeks. Conclusion Injection of BTX-A guided by peripheral nerve stimulation is effective on hemifacial spasm for a long time.

Key words: hemifacial spasm, Botulinum toxin A, peripheral nerve stimulation