肠-脑轴在脑缺血中作用的研究进展

doi:10.3969/j.issn.1006-9771.2020.07.011

摘要/Abstract

摘要：

过去十年,人们对肠道微生物群的兴趣越来越大,尤其是肠-脑轴。肠-脑轴是一个通过多途径循环反馈环路,涉及中枢神经系统、自主神经系统、肠神经系统和下丘脑-垂体-肾上腺轴,多种信号分子。肠道微生物群是启动脑损伤神经炎症反应的关键调节因子,可能加重脑卒中病情或起保护作用。

关键词: 肠道微生物群, 肠-脑轴, 中枢神经系统, 综述

Abstract:

In the past decade, more and more researches interested in the intestinal microbial populations, especially the gut-brain axis. Gut-brain axis is feedback loop cycle with a variety of routes than a linear system, involving the central nervous system, autonomic nervous system, enteric nervous system and hypothalamic-pituitary-adrenal axis, and many signal molecules. The intestinal microbiota plays a key role to start cerebral inflammation, which may be harmful or protective after stroke.

Key words: gut microbiota, gut-brain axis, central nervous system, review

中图分类号:

R743.3

杨赫,唐强,陈秋欣. 肠-脑轴在脑缺血中作用的研究进展[J]. 《中国康复理论与实践》, 2020, 26(7): 793-796.

YANG He,TANG Qiang,CHEN Qiu-xin. Advances in Gut-brain Axis in Cerebral Ischemia (review)[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2020, 26(7): 793-796.

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