《中国康复理论与实践》

《中国康复理论与实践》

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应用高分辨率磁共振成像评估脑动脉粥样硬化斑块的研究进展①

于瑾1,2a，白皛2b，吴士文2a，徐蔚海3，吴卫平1   

  1. 1.解放军总医院老年神经内科，北京市100853；2.武警总医院，a.神经内科；b.南一科，北京市100039；3.中国医学科学院北京协和医院神经科，北京市100730。
  • 出版日期:2016-02-25 发布日期:2016-06-01

Progress of High- resolution Magnetic Resonance Imaging in Evaluating Cerebral Atherosclerotic Plaques (review)

YU Jin1,2a, BAI Xiao2b, WU Shi-wen2a, XU Wei-hai3, WU Wei-ping1   

  1. 1. Department of Geriatric Neurology, People's Liberation Army General Hospital, Beijing 100853, China; 2. a. Department of Neurology; b. Department of Cadre Ward, General Hospital of Chinese People's Armed Police Forces, Beijing 100039, China; 3. Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China
  • Published:2016-02-25 Online:2016-06-01

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摘要： 高分辨率磁共振成像(HRMRI)是一项安全、无创、经济和可重复的检查方法，可以精确反映动脉粥样硬化的程度，对未来的临床事件有较高的预测价值。其核磁扫描像素可达到亚毫米级，采用“黑血” 技术，广泛应用于动脉管壁及斑块成分的研究。应用HRMRI评估脑动脉粥样硬化斑块的易损性，包括动脉重塑、斑块负荷、斑块内出血和强化、斑块分布等特点，具有重要的临床意义。

关键词: 高分辨率, 磁共振成像, 脑动脉, 动脉粥样硬化, 斑块, 综述

Abstract: High-resolution magnetic resonance imaging (HRMRI) is a safe, non-invasive, inexpensive, accurate and reproducible clinical imaging modality, and the results can acutely reflect the extent of atherosclerotic disease and have high predictive values for future clinical events. It uses black blood imaging techniques and can obtain sufficient sensitivity for submillimetre imaging. HRMRI has been used widely to visualize the vessel wall and differentiate the components of atherosclerotic plaques. It is of important clinical meaning to evaluate plaque vulnerability with HRMRI, which is related to the remodeling pattern, plaque burden, intraplaque hemorrhage and contrast enhancement, and plaque distribution, etc.

Key words: high-resolution, magnetic resonance imaging, cerebral arteries, atherosclerosis, plaque, review