阈值负荷吸气肌训练对慢性阻塞性肺疾病患者呼吸功能、运动功能及生活质量影响的Meta分析

doi:10.3969/j.issn.1006-9771.2022.09.004

《中国康复理论与实践》 ›› 2022, Vol. 28 ›› Issue (9): 1022-1031.doi: 10.3969/j.issn.1006-9771.2022.09.004

• 专题身体活动与运动康复 • 上一篇下一篇

阈值负荷吸气肌训练对慢性阻塞性肺疾病患者呼吸功能、运动功能及生活质量影响的Meta分析

彭娟^1,a²,王洁萍^1,a²,黄炜^1b,樊必双^1,a²,虞记华^1,a²,曾今^1,a²,黄丽衡^1,a²,安丽娟^1,a²,胥方元^1,a²()

1.西南医科大学附属医院, a. 康复医学科; b. 内分泌与代谢内科, 四川泸州市 646000
2.西南医科大学康复医学系,四川泸州市 646000

收稿日期:2021-10-11 修回日期:2022-04-28 出版日期:2022-09-25 发布日期:2022-10-08
通讯作者: 胥方元 E-mail:x5144@163.com
作者简介:彭娟(1988-),女,汉族,四川泸州市人,硕士,主治医师,主要研究方向：心肺康复。|胥方元(1971-),男,汉族,四川泸州市人,硕士,教授,主任医师,硕士生导师,主要研究方向：神经康复及骨科康复。
基金资助:
泸州市人民政府-西南医科大学科技战略合作项目(2019LZXNYDJ40);四川省泸州市科技计划应用基础研究项目(2018-JYJ-43);四川省卫生健康委员会科研课题(19PJ294)

Effects of threshold inspiratory muscle training on respiratory function, motor function and quality of life for patients with chronic obstructive pulmonary disease: a meta-analysis

PENG Juan^1,a²,WANG Jieping^1,a²,HUANG Wei^1b,FAN Bishuang^1,a²,YU Jihua^1,a²,ZENG Jin^1,a²,HUANG Liheng^1,a²,AN Lijuan^1,a²,XU Fangyuan^1,a²()

1.a. Department of Rehabilitaion; b. Department of Endocrinology and Metabolism, the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China
2. Department of Rehabilitation Medicine, Southwest Medical University, Luzhou, Sichuan 646000, China

Received:2021-10-11 Revised:2022-04-28 Published:2022-09-25 Online:2022-10-08
Contact: XU Fangyuan E-mail:x5144@163.com
Supported by:
Technology Cooperation Project of Luzhou Municipal People's Government and Southwest Medical University(2019LZXNYDJ40);Basic Research Project of Luzhou Science and Technology Program(2018-JYJ-43);Scientific Research Project of Sichuan Health Committee(19PJ294)

摘要/Abstract

摘要：

目的系统分析阈值负荷吸气肌训练(TIMT)对慢性阻塞性肺疾病(COPD)患者呼吸、运动功能及生活质量的影响。
方法从PubMed、EBSCO、Web of Science、Ovid、Cochrane Library、中国生物医学文献数据库、中国知网和维普数据库检索自建库至2020年9月关于TIMT对COPD患者呼吸、运动功能及生活质量影响的随机对照试验(RCT)。由两名研究者独立进行文献筛选、资料提取和质量评价,采用RevMan 5.3软件进行Meta分析。
结果共纳入30个RCT,2 060例患者。TIMT能显著增加最大吸气压(MD = 10.68, 95%CI 7.43~13.92, P < 0.001),改善6分钟步行试验结果(MD = 24.62, 95%CI 9.09~40.15, P = 0.002)、圣乔治呼吸疾病问卷评分(MD = -3.08, 95%CI -5.84~-0.33, P = 0.03)、改良英国医学会研究协会呼吸困难量表评分(MD = -0.30, 95%CI -0.52~-0.07, P = 0.01)和Borg评分(MD = -0.84, 95%CI -1.24~-0.44, P < 0.001)。TIMT能改善第1秒用力最大呼气容积(MD = 0.11, 95%CI 0.04~0.19, P = 0.003)和第1秒钟用力呼气容积占预计值百分比(MD = 3.72, 95%CI 2.62~4.82, P < 0.001)。TIMT对COPD评估测试评分(MD = -1.14, 95%CI -2.32~0.03, P = 0.06)和用力肺活量(MD = 0.07, 95%CI -0.12~0.25, P = 0.49)无显著改善作用。
结论 TIMT能够提升COPD患者吸气肌肌力,缓解呼吸困难,提升患者肺功能、生活质量及运动能力。

关键词: 阈值负荷吸气肌训练, 慢性阻塞性肺疾病, 随机对照试验, Meta分析

Abstract:

Objective To systematically evaluate the effects of threshold inspiratory muscle training (TIMT) on respiratory function, motor function and quality of life in patients with chronic obstructive pulmonary disease (COPD).
Methods Randomized controlled trials (RCT) about the effects of TIMT on dyspnea, quality of life, motor function and inspiratory muscle strength for COPD patients were retrieved from PubMed, EBSCO, Web of Science, Ovid, Cochrane Library, SinoMed, CNKI, VIP, since establishment to September, 2020. Two researchers independently screened literatures, extracted data and evaluated the methodological quality. A meta-analysis was performed using RevMan 5.3.
Results A total of 30 RCTs involving 2 060 patients were included. TIMT could obviously improve the maximum inspiratory pressure (MD = 10.68, 95%CI 7.43 to 13.92, P< 0.001), optimize the results of 6-minute Walking Test (MD = 24.62, 95%CI 9.09 to 40.15, P= 0.002), the St George's Respiratory Questionnaire (MD = -3.08, 95%CI -5.84 to -0.33, P= 0.03), the modified Medical Research Council Dyspnea Scale (MD = -0.30, 95%CI -0.52 to -0.07, P= 0.01) and Borg score (MD = -0.84, 95%CI -1.24 to -0.44, P< 0.001). TIMT could also improve the forced expiratory volume in one second (MD = 0.11, 95%CI 0.04 to 0.19, P= 0.003) and the forced expiratory volume in one second in predicted (MD = 3.72, 95%CI 2.62 to 4.82, P< 0.001). There was no significant difference in the COPD Assessment Test (MD = -1.14, 95%CI -2.32 to 0.03, P= 0.06) or forced vital capacity (MD = 0.07, 95%CI -0.12 to 0.25, P= 0.49).
Conclusion TIMT can improve the inspiratory muscle strength, alleviate the symptoms of dyspnea, and improve the lung function and the quality of life for COPD patients.

Key words: threshold inspiratory muscle training, chronic obstructive pulmonary disease, randomized controlled trial, meta-analysis

中图分类号:

R563.3

彭娟,王洁萍,黄炜,樊必双,虞记华,曾今,黄丽衡,安丽娟,胥方元. 阈值负荷吸气肌训练对慢性阻塞性肺疾病患者呼吸功能、运动功能及生活质量影响的Meta分析[J]. 《中国康复理论与实践》, 2022, 28(9): 1022-1031.

PENG Juan,WANG Jieping,HUANG Wei,FAN Bishuang,YU Jihua,ZENG Jin,HUANG Liheng,AN Lijuan,XU Fangyuan. Effects of threshold inspiratory muscle training on respiratory function, motor function and quality of life for patients with chronic obstructive pulmonary disease: a meta-analysis[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2022, 28(9): 1022-1031.

图/表 10

图1

表1

纳入研究的基本特征"

纳入研究	国家/地区	研究对象/n	年龄/岁	性别 (男/女)/n	肺功能分级	干预时间	干预措施	评定时间	结局指标	PEDro 评分	文献质量
郑江南等^[7](2019)	中国	T:25 C:25	T:64.76±5.51 C:65.56±5.79	T:16/9 C:15/10	未提及	30次呼吸/组,休息2 min/15次呼吸,2组/天,每周5 d,共48周	T:TIMT+支气管扩张剂/糖皮质激素 C:空白对照+支气管扩张剂/糖皮质激素	训练前训练48周后	(1)(2)(3)(4)(5)(6)	6	高
黄玉霞等^[8](2018)	中国	T:21 C:20	未提及	T:16/5 C:14/6	未提及	每次锻炼3 min,休息2 min,8次/组,共8周	T:TIMT+常规药物 C:空白对照+常规药物	训练前训练8周后	(1)(3)(5)(7)(8)	7	高
黄元萍等^[9](2019)	中国	T:40 C:40	T:64.37±11.35 C:66.69±10.46	T:28/12 C:24/16	未提及	每次锻炼3 min,休息5 min,每组8次,共8周	T:TIMT+常规药物 C:空白对照+常规药物	训练前训练8周后	(2)(3)(4)(5)(8)(9)	6	高
闫立娟等^[10](2019)	中国	T:68 C:68	T:63.85±2.5 C:63.46±2.37	T:40/28 C:42/26	Ⅱ~Ⅳ级	每次20 min,每天2次,共5周	T:TIMT+常规药物 C:呼吸操+常规药物	训练前训练5周后	(1)(2)(3)(4)(9)(10)	6	高
徐建红等^[11](2014)	中国	T:23 C:22	T:65.30±3.41 C:66.78±3.52	T:15/8 C:16/6	I~II级	每次15 min,每天1次,共24周	T:有氧训练+TIMT C:有氧训练+假性干预	训练前训练24周后	(1)(3)(10)	6	高
陈长芳等^[12](2016)	中国	T:32 C:31	T:68.95±7.93 C:67.33±7.86	未提及	未提及	每次15 min,每天2次,每周6 d,共48周	T:支气管扩张剂/糖皮质激素+TIMT C:支气管扩张剂/糖皮质激素+假性干预	训练前训练48周后	(2)(3)(4)(7)(9)	6	高
Xu等^[13](2018)	中国	T:23 C:23	T:67.49±6.17 C:69.43±6.44	未提及	Ⅱ~Ⅳ级	每天48 min,每周7 d,共8周	T:TIMT+常规药物 C:假性干预+常规药物	训练前训练8周后	(1)(7)(8)(5)(3)(2)(9)(4)(11)(12)	7	高
Wu等^[14](2017)	中国	T:21 C:19	T:62.24±7.36 C:60.30±6.55	未提及	未提及	每次15 min,每天2次,共8周	T:TIMT+常规药物 C:空白对照+常规药物	训练前训练8周后	(3)(13)(14)(15)	7	高
Weiner等^[15](1992)	以色列	T:12 C:12	T:67.2 ±2.6 C:64.4 ±3.0	T:6/6 C:7/5	稳定型	每次60 min,每周3次,共24周	T:TIMT+一般训练 C:假性干预+一般训练	训练前训练24周后	(2)(3)(8)(9)(16)	6	高
Wang等^[16](2017)	中国	T:28 C:27	T:70.8±4.5 C:70.0±6.3	未提及	未提及	每次30 min CET训练+14 min TIMT,每周3次,共8周	T:TIMT+循环呼吸训练 C:空白对照+循环呼吸训练	训练前训练8周后	(1)(2)(3)(4)(5)(7)(8)(9)(11)(12)(17)(18)	9	极高
Schultz等^[17](2018)	德国	T:300 C:302	T:57.7±8.2 C:57.9±6.6	T:188/112 C:201/101	II~IV级	每天21 min,每周7 d,共3周	T:肺康复计划+TIMT C:肺康复计划+假性干预	训练前训练3周后	(1)(7)(3)(2)(5)(14)(19)(20)	6	高
Sánchez等^[18](2001)	西班牙	T:10 C:10	T:67±4 C:67.6±5	T:9/1 C:9/1	未提及	每次20 min,每天2次,每周6 d,共24周	T:TIMT+常规药物 C:假性干预+常规药物	训练前训练24周后	(3)(10)(14)(15)(21)(22)(23)(24)(25)	8	高
Margaret等^[19](2001)	美国	T:12 C:15	T:65±6 C:67±10	未提及	严重型	每天30 min,每周5 d,共16周	T:TIMT+健康教育 C:空白对照+健康教育	训练前训练16周后	(3)(15)(26)	8	高
Hsiao等^[20] (2003)	中国	T:10 C:10	T:68.2±6.5 C:71.1±3.9	T:10/0 C:8/2	中到重度	每天15 min,每周5 d,共8周	T:TIMT C:假性干预	训练前训练8周后	(1)(3)(27)	6	高
Beckerman等^[21](2005)	以色列	T:21 C:21	T:67.7±3.6 C:66.9±3.3	T:17/4 C:15/6	未提及	每次15 min,每天2次,每周6 d, 共48周	T:TIMT C:假性干预	训练前训练12周、24周、36周、48周后	(1)(3)(7)(10)(28)(29)(30)	8	高
Langer等^[22] (2018)	加拿大	T:10 C:10	T: 73±4 C:67±8	T:4/6 C:3/7	中到重度	每组4~5 min,每天2~3组,每周7 d,共8周	T:TIMT C:假性干预	训练前训练8周后	(3)(10)(8)(13)(14)	9	极高
Abedi等^[23](2019)	伊朗	T:16 C:15	T:51.88±9.05 C:55.67±11.08	T:7/9 C:7/8	中到重度	每天15 min,每周2 d,共8周	T:TIMT+常规药物 C:空白对照+常规药物	训练前训练4周、8周后	(7)	5	中
Kim等^[24] (1993)	美国	T:41 C:26	T:66±7 C:63±8	未提及	中到重度	每天30 min,共24周	T:TIMT C:假性干预	训练前训练12周、24周后	(3)(16)	7	高
Lisboa等^[25](1997)	智利	T:10 C:10	T:61±2 C:64±2	T:6/4 C:7/3	未提及	每天30 min,每周6 d,共10周	T:TIMT C:假性干预	训练前训练10周后	(1)(2)(3)(9)(10)(14)(25)	8	高
Basso-Vanelli等^[26](2016)	巴西	T:13 C:12	T:67±12.8 C:66±7.6	T:11/2 C:9/3	中到重度	每天21 min,每周3 d,共16周	T:体能训练+TIMT C:体能训练+健美操呼吸训练	训练前训练16周后	(1)(2)(3)(4)(8)(9)(14)(17)(31)	6	高
Bavarsad等^[27](2015)	伊朗	T:15 C:15	T:58.8±6.82 C:54.2±8.09	T:13/2 C:14/1	中到重度	每天15 min,每周6 d,共8周	T: TIMT+常规药物 C: 空白对照+常规药物	训练前训练8周后	(1)(2)(4)(9)(10)	5	中
Beaumont等^[28](2018)	法国	T:74 C:75	T:62.2±8.0 C:65.9±8.9	T:30/44 C:25/50	重度	每天15 min,每周5 d,共4周	T: 肺康复计划+TIMT C: 肺康复计划+空白对照	训练前训练4周后	(1)(2)(3)(7)(8)(10)(32)(33)	8	高
Beaumont等^[29](2015)	法国	T:16 C:18	T:62±10 C:61±7	T:4/12 C:7/11	中到重度	每组15 min,每天2组,每周5 d,共3周	T: 肺康复计划+TIMT C: 肺康复计划+空白对照	训练前训练3周后	(1)(3)(10)(31)(32)(34)	7	高
Charususin等^[30](2018)	比利时	T:89 C:85	T:66±8 C:65±7	未提及	未提及	每次3~5 min,每天2次,共8周	T: 肺康复计划+TIMT C: 肺康复计划+假性干预	训练前训练8周后	(1)(3)(17)(18)(22)(35)	8	高
Chuang等^[31](2017)	中国	T:27 C:28	T:66.22±12.76 C:66.04±10.99	T:17/10 C:19/9	中到重度	每天21~30 min,每周5 d,共8周	T:TIMT+常规药物及护理 C:空白对照+常规药物及护理	训练前训练4周、8周后	(1)(3)(13)(27)	5	中
Cutrim等^[32](2019)	巴西	T:11 C:11	T:70±8 C:66±8.5	T:9/2 C:8/3	未提及	每周3 d,共12周	T:TIMT C:空白对照	训练前训练12周后	(1)(2)(3)(9)(18)	8	高
Hill等^[33] (2006)	澳大利亚	T:16 C:17	T:69.4±7.2 C:66.6±9.8	T:11/5 C:11/6	中到重度	每天21 min,每周3 d,共8周	T:TIMT C:假性干预	训练前训练8周后	(1)(2)(3)(4)(9)(15)(18)(33)	7	高
Nikoletou等^[34](2016)	英国	T:22 C:19	T:70.1±8.4 C:71.1±9.6	T:13/9 C:11/8	中到重度	每天2次,每周6 d,共7周	T:TIMT C:空白对照	训练前训练7周后	(3)(11)(15)(21)(27)(36)(37)	7	高
Weiner等^[35] (2006)	以色列	T:14 C:14	未提及	T:8/6 C:8/6	中到重度	每天60 min,每周6 d,共8周	T:TIMT C:假性干预	训练前训练8周后	(3)(38)	8	高
Elmorsi等^[36](2016)	埃及	T:20 C:20	T:57.20±5.08 C:55.70±6.12	未提及	中到重度	每天3 min,每周6 d,共8周	T:TIMT+常规药物 C:空白对照+常规药物	训练前训练4周、8周后	(1)(3)(7)(8)(22)	5	中

表1

图2

图3

图4

图5

图6

图7

图8

图9

参考文献 46

[1]	ZAGACETA J, BASTARRIKA G, ZULUETA J, et al. Prospective comparison of non-invasive risk markers of major cardiovascular events in COPD patients[J]. Respir Res, 2017, 18(1): 175. doi: 10.1186/s12931-017-0658-y
[2]	李为民, 罗汶. 我国慢性呼吸系统疾病的防治现状[J]. 西部医学, 2020, 32(1): 1-4.
	LI W M, LUO W. Progress in the prevention and treatment of chronic respiratory diseases[J]. Med J West Chin, 2020, 32(1): 1-4.
[3]	NICI L, DONNER C, WOUTERS E, et al. American Thoracic Society/European Respiratory Society statement on pulmonary rehabilitation[J]. Am J Respir Crit Care Med, 2006, 173(12): 1390-1413. doi: 10.1164/rccm.200508-1211ST
[4]	时惠, 刘玲, 祖菲娅·吐尔迪. 阈值压力负荷呼吸肌训练对脑卒中患者康复疗效的Meta分析[J]. 中国康复理论与实践, 2016, 22(9): 1069-1074.
	SHI H, LIU L, TURDI Z F Y. Threshold training of respiratory muscles after stroke: a meta-analysis[J]. Chin J Rehabil Theory Pract, 2016, 22(9): 1069-1074.
[5]	DIXIT A, PRAKASH S. Effects of threshold inspiratory muscle training versus conventional physiotherapy on the weaning period of mechanically ventilated patients: a comparative study[J]. Int J Physiother Res, 2014, 2(2): 424-428.
[6]	吴雨晨, 丁楠楠, 姜变通, 等. 阈值负荷吸气肌训练对呼吸肌功能影响的Meta分析[J]. 中国康复理论与实践, 2019, 25(10): 1150-1161.
	WU Y C, DING N N, JIANG B T, et al. Effect of threshold inspiratory muscle training on respiratory muscle function: a meta-analysis[J]. Chin J Rehabil Theory Pract, 2019, 25(10): 1150-1161.
[7]	郑江南, 肖颖, 邹兆华, 等. 吸气肌训练在慢性阻塞性肺疾病中的康复效果评价[J]. 天津医药, 2019, 47(7): 735-738.
	ZHENG J N, XIAO Y, ZOU Z H, et al. The value of inspiratory muscle training as a rehabilitation treatment in patients with chronic obstructive pulmonary disease[J]. Tianjin Med J, 2019, 47(7): 735-738.
[8]	黄玉霞, 陈宜泰, 徐文慧, 等. 比较单一吸气肌和吸呼肌联合阈值负荷锻炼在慢性阻塞性肺疾病肺康复中的效果: 随机对照试验[J]. 中国康复医学杂志, 2018, 33(8): 975-978.
	HUANG Y X, CHEN Y T, XU W H, et al. Comparison of the effects of single Inspiratory muscle and Respiratory muscles combined with threshold load exercise in pulmonary rehabilitation of chronic obstructive pulmonary disease: a randomised controlled trial[J]. Chin J Rehabil Med, 2018, 33(8): 975-978.
[9]	黄元萍, 李永春, 邓长锋, 等. 不同方式呼吸肌阈值负荷锻炼对稳定期慢性阻塞性肺疾病患者呼吸生理学指标的影响[J]. 临床内科杂志, 2019, 36(8): 543-546.
	HUANG Y P, LI Y C, DENG C F, et al. Effect of different respiratory muscle threshold load training on the respiratory physiological indexes in patients with stable chronic obstructive pulmonary disease[J]. J Clin Int Med, 2019, 36(8): 543-546.
[10]	闫立娟, 赵新华, 张雪莹, 等. 阈值压力负荷呼吸肌训练对慢性阻塞性肺疾病患者呼吸康复及生存质量的影响分析[J]. 贵州医药, 2019, 43(2): 261-264.
	YAN L J, ZHAO X H, ZHANG X Y, et al. Effect of threshold stress-load respiratory muscle training on respiratory rehabilitation and quality of life in patients with chronic obstructive pulmonary disease[J]. Guizhou Med J, 2019, 43(2): 261-264.
[11]	徐建红, 施加加. 渐进阻荷吸气肌训练对慢性阻塞性肺疾病患者的影响[J]. 中国康复, 2014, 29(5): 375-376.
	XU J H, SHI J J. Effects of progressive inspiratory muscle training on patients with chronic obstructive pulmonary disease[J]. Chin J Rehabil, 2014, 29(5): 375-376.
[12]	陈长芳, 梅桃桃, 陈秀利, 等. 长期最大负荷吸气肌训练改善稳定期COPD患者吸气肌力和生活质量[J]. 南京医科大学学报(自然科学版), 2016, 36(3): 350-352.
	CHEN C F, MEI T T, CHEN X L, et al. Long-term maximum load inspiratory muscle training improves inspiratory muscle strength and quality of life in patients with stable COPD[J]. J Nanjing Med Univ, 2016, 36(3): 350-352.
[13]	XU W H, LI R, GUAN L L, et al. Combination of inspiratory and expiratory muscle training in same respiratory cycle versus different cycles in COPD patients: a randomized trial[J]. Respir Res, 2018, 19(1): 225-235. doi: 10.1186/s12931-018-0917-6
[14]	WU W, GUAN L, ZHANG X, et al. Effects of two types of equal-intensity inspiratory muscle training in stable patients with chronic obstructive pulmonary disease: a randomised controlled trial[J]. Respir Med, 2017, (132): 84-91.
[15]	WEINER P, AZGAD Y, GANAM R, et al. Inspiratory muscle training combined with general exercise reconditioning in patients with COPD[J]. Chest, 1992, 102(5): 1351-1356. pmid: 1424850
[16]	WANG K, ZENG G Q, LI R, et al. Cycle ergometer and inspiratory muscle training offer modest benefit compared with cycle ergometer alone: a comprehensive assessment in stable COPD patients[J]. Int J Chron Obstruct Pulmon Dis, 2017, 12: 2655-2668. doi: 10.2147/COPD.S140093
[17]	SCHULTZ K, JELUSIC D, WITTMANN M, et al. Inspiratory muscle training does not improve clinical outcomes in 3-week COPD rehabilitation: results from a randomised controlled trial[J]. Eur Respir J, 2018, 51(1): 1702000. doi: 10.1183/13993003.02000-2017
[18]	SÁNCHEZ RIERA H, MONTEMAYOR RUBIO T, ORTEGA RUIZ F, et al. Inspiratory muscle training in patients with COPD: effect on dyspnea, exercise performance, and quality of life[J]. Chest, 2001, 120(3): 748-756. pmid: 11555505
[19]	MARGARET K C, JANET L L, SCOTT E, et al. High-intensity inspiratory muscle training in patients with chronic obstructive pulmonary disease and severely reduced function[J]. J Cardiopulm Rehabil, 2001, 21(4): 231-240. pmid: 11508185
[20]	HSIAO S F, WU Y T, WU H D, et al. Comparison of effectiveness of pressure threshold and targeted resistance devices for inspiratory muscle training in patients with chronic obstructive pulmonary disease[J]. J Formos Med Assoc, 2003, 102(4): 240-245.
[21]	BECKERMAN M, MAGADLE R, WEINER M, et al. The effects of 1 year of specific inspiratory muscle training in patients with COPD[J]. Chest, 2005, 128(5): 3177-3182. pmid: 16304259
[22]	LANGER D, CIAVAGLIA C, FAISAL A, et al. Inspiratory muscle training reduces diaphragm activation and dyspnea during exercise in COPD[J]. J Appl Physiol (1985), 2018, 125(2): 381-392. doi: 10.1152/japplphysiol.01078.2017
[23]	ABEDI YEKTA A H, POURSAEID ESFAHANI M, SALEHI S, et al. Assessment of the effects of inspiratory muscle training (IMT) and aerobic training on the quality of life of patients with chronic obstructive pulmonary disease[J]. Tanaffos, 2019, 18(3): 223-229.
[24]	KIM M J, LARSON J L, COVEY M K, et al. Inspiratory muscle training in patients with chronic obstructive pulmonary disease[J]. Nurs Res, 1993, 42(6): 356-362. pmid: 8247819
[25]	LISBOA C, VILLAFRANCA C, LEIVA A, et al. Inspiratory muscle training in chronic airflow limitation: effect on exercise performance[J]. Eur Respir J, 1997, 10(3): 537-542. pmid: 9072981
[26]	BASSO-VANELLI R P, DI LORENZO V A, LABADESSA I G, et al. Effects of inspiratory muscle training and calisthenics-and-breathing exercises in COPD with and without respiratory muscle weakness[J]. Respir Care, 2016, 61(1): 50-60. doi: 10.4187/respcare.03947
[27]	BAVARSAD M B, SHARIATI A, EIDANI E, et al. The effect of home-based inspiratory muscle training on exercise capacity, exertional dyspnea and pulmonary function in COPD patients[J]. Iran J Nurs Midwifery Res, 2015, 20(5): 613-618. doi: 10.4103/1735-9066.164588 pmid: 26457101
[28]	BEAUMONT M, MIALON P, LE BER C, et al. Effects of inspiratory muscle training on dyspnoea in severe COPD patients during pulmonary rehabilitation: controlled randomised trial[J]. Eur Respir J, 2018, 51(1): 1701107. doi: 10.1183/13993003.01107-2017
[29]	BEAUMONT M, MIALON P, LE BER-MOY C, et al. Inspiratory muscle training during pulmonary rehabilitation in chronic obstructive pulmonary disease: a randomized trial[J]. Chron Respir Dis, 2015, 12(4): 305-312. doi: 10.1177/1479972315594625
[30]	CHARUSUSIN N, GOSSELINK R, DECRAMER M, et al. Randomised controlled trial of adjunctive inspiratory muscle training for patients with COPD[J]. Thorax, 2018, 73(10): 942-950. doi: 10.1136/thoraxjnl-2017-211417 pmid: 29914940
[31]	CHUANG H Y, CHANG H Y, FANG Y Y, et al. The effects of threshold inspiratory muscle training in patients with chronic obstructive pulmonary disease: a randomised experimental study[J]. J Clin Nurs, 2017, 26(23/24): 4830-4838. doi: 10.1111/jocn.13841
[32]	CUTRIM A L C, DUARTE A A M, SILVA-FILHO A C, et al. Inspiratory muscle training improves autonomic modulation and exercise tolerance in chronic obstructive pulmonary disease subjects: a randomized-controlled trial[J]. Respir Physiol Neurobiol, 2019, 263: 31-37. doi: S1569-9048(19)30016-3 pmid: 30853602
[33]	HILL K, JENKINS S C, PHILIPPE D L, et al. High-intensity inspiratory muscle training in COPD[J]. Eur Respir J, 2006, 27(6): 1119-1128. pmid: 16772388
[34]	NIKOLETOU D, MAN W D, MUSTFA N, et al. Evaluation of the effectiveness of a home-based inspiratory muscle training programme in patients with chronic obstructive pulmonary disease using multiple inspiratory muscle tests[J]. Disabil Rehabil, 2016, 38(3): 250-259. doi: 10.3109/09638288.2015.1036171 pmid: 25885668
[35]	WEINER P, WEINER M. Inspiratory muscle training may increase peak inspiratory flow in chronic obstructive pulmonary disease[J]. Respiration, 2006, 73(2): 151-156. pmid: 16155355
[36]	ELMORSI A S, ELDESOKY M E, MOHSEN M A A, et al. Effect of inspiratory muscle training on exercise performance and quality of life in patients with chronic obstructive pulmonary disease[J]. Egypt J Chest Dis Tuberc, 2016, 65(1): 41-46. doi: 10.1016/j.ejcdt.2015.10.006
[37]	BEAUMONT M, FORGET P, COUTURAUD F, et al. Effects of inspiratory muscle training in COPD patients: a systematic review and meta‐analysis[J]. Clin Respir J, 2018, 12(7): 2178-2188. doi: 10.1111/crj.12905
[38]	王娟, 朱芬, 王朴, 等. 重复经颅磁刺激治疗脑卒中后患者肢体运动功能障碍的系统评价[J]. 中国循证医学杂志, 2012, 12(12): 1478-1488.
	WANG J, ZHU F, WANG P, et al. Effectiveness of repetitive transcranial magnetic stimulation in stroke patients with motor dysfunction: a systematic review[J]. Chin J Evid Based Med, 2012, 12(12): 1478-1488.
[39]	MAGADLE R, MCCONNELL A K, BECKERMAN M, et al. Inspiratory muscle training in pulmonary rehabilitation program in COPD patients[J]. Respir Med, 2007, 101(7): 1500-1505. doi: 10.1016/j.rmed.2007.01.010
[40]	MAJEWSKA-PULSAKOWSKA M, WYTRYCHOWSKI K, ROŻEK-PIECHURA K. The role of inspiratory muscle training in the process of rehabilitation of patients with chronic obstructive pulmonary disease[J]. Adv Exp Med Biol, 2016, 885: 47-51.
[41]	LANGER D, JACOME C, HOFFMAN M, et al. Comparison of two high intensity inspiratory muscle training programs in patients with COPD: a randomized controlled trial[J]. Am J Respir Crit Care Med, 2013, 20(3): 187-196.
[42]	AHMAD H, JUSTINE M, OTHMAN Z, et al. The outcomes of short term inspiratory muscle training (IMT) combined with chest physiotherapy in hospitalized COPD patients[J]. Bangl J Med Sci, 2013, 12(4): 398-404.
[43]	GEDDES E L, REID W D, CROWE J, et al. Inspiratory muscle training in adults with chronic obstructive pulmonary disease: a systematic review[J]. Respir Med, 2005, 99(11): 1440-1458. doi: 10.1016/j.rmed.2005.03.006
[44]	MCCONNELL A K, ROMER L M, WEINER P. Inspiratory muscle training in obstructive lung disease: how to implement and what to expect[J]. Breathe, 2005, 2(1): 38-49. doi: 10.1183/18106838.0201.38
[45]	POWERS S K, CRISWELL D. Adaptive strategies of respiratory muscles in response to endurance exercise[J]. Med Sci Spots Exerc, 1996, 28(9): 1115-1122.
[46]	SHOEMAKER M J, DONKER S, LAPOE A. Inspiratory muscle training in patients with chronic obstructive pulmonary disease: the state of the evidence[J]. Cardiopulm Phys Ther J, 2009, 20(3): 5-15. pmid: 20467518

阈值负荷吸气肌训练对慢性阻塞性肺疾病患者呼吸功能、运动功能及生活质量影响的Meta分析

Effects of threshold inspiratory muscle training on respiratory function, motor function and quality of life for patients with chronic obstructive pulmonary disease: a meta-analysis

RichHTML

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

图/表 10

参考文献 46

相关文章 15

Metrics

本文评价

推荐阅读 0

[1]	王贺, 韩靓, 阚梦凡, 于少泓. 电刺激治疗脑卒中后肩手综合征有效性的系统评价与Meta分析[J]. 《中国康复理论与实践》, 2023, 29(9): 1048-1056.
[2]	唐流泉, 彭兴云. 血流限制下运动对绝经后慢性阻塞性肺疾病患者脆性骨折部分危险因素的疗效[J]. 《中国康复理论与实践》, 2023, 29(7): 761-769.
[3]	于歌, 王璐, 陈亚平. 全身振动训练对慢性踝关节不稳姿势稳定性影响的Meta分析[J]. 《中国康复理论与实践》, 2023, 29(4): 423-432.
[4]	张丽英, 王杰宁, 于小明. 机器人辅助训练对脑卒中患者上肢运动功能效果的Meta分析[J]. 《中国康复理论与实践》, 2023, 29(2): 156-166.
[5]	孙喜妹, 刘华, 柴良伟, 李凯洋, 马景. 治疗性运动对头前倾并发颈痛患者颈部功能和生活质量影响的Meta分析[J]. 《中国康复理论与实践》, 2023, 29(2): 214-222.
[6]	任开新,李灵聪,王秀静,马力颖,王振宇. 肩袖损伤非手术治疗效果中情景效应比例的Meta分析[J]. 《中国康复理论与实践》, 2022, 28(9): 1039-1048.
[7]	张博超,杨朝,郭立泉,陈静,熊大曦. 基于机器学习的慢性阻塞性肺疾病急性加重预测模型的研究[J]. 《中国康复理论与实践》, 2022, 28(6): 678-683.
[8]	徐振,王一迪,张月,温宇红. 运动干预对多发性硬化患者疲劳症状影响的Meta分析[J]. 《中国康复理论与实践》, 2022, 28(5): 568-577.
[9]	郑尉,孙立冰,郝传萍,黄文琪,尤婧,郭彦桦. 脊柱手法治疗对慢性非特异性颈痛干预效果的Meta分析[J]. 《中国康复理论与实践》, 2022, 28(2): 150-164.
[10]	柴良伟,刘华,黄秋玉,孙喜妹,李凯洋,马景. 治疗性运动对功能性踝关节不稳姿势控制和踝周肌肉功能影响的Meta分析[J]. 《中国康复理论与实践》, 2022, 28(11): 1278-1287.
[11]	李欣欣,刘卉,马沐佳. 太极拳与其他运动降低老年人跌倒风险的Meta分析[J]. 《中国康复理论与实践》, 2022, 28(10): 1169-1177.
[12]	柯竟悦,马圣楠,张晓慧,李古强. 青少年特发性脊柱侧凸患者静态站立及步行时生物力学变化的Meta分析[J]. 《中国康复理论与实践》, 2022, 28(10): 1178-1189.
[13]	刘阳,张孝权,王恒,齐莉萍. 虚拟现实技术对帕金森病患者综合平衡能力改善的Meta分析[J]. 《中国康复理论与实践》, 2021, 27(9): 1048-1058.
[14]	蔡倩,张溪,荆纯祥,蔡书宾,郭明凯,李际强. 弹性抗阻运动对慢性阻塞性肺疾病康复疗效的Meta分析[J]. 《中国康复理论与实践》, 2021, 27(8): 913-922.
[15]	李玲玲,于莹,贾雨琦,黄海量. 脑机接口对脑卒中后上肢运动功能效果的Meta分析[J]. 《中国康复理论与实践》, 2021, 27(7): 765-773.