[1] Ellis-Davies GC. Two-photon microscopy for chemical neuroscience [J]. ACS Chem Neurosci, 2011, 2(4): 185-197.
[2] Iyer M, Berenji M, Templeton NS, et al. Noninvasive imaging of cationic lipid-mediated delivery of optical and PET reporter genes in living mice [J]. Mol Ther, 2002, 6(4): 555-562.
[3] Danthi SN, Pandit SD, Li KC. A primer on molecular biology for imagers: VII. Molecular imaging probes [J]. Acad Radiol, 2004, 11(9): 1047-1054.
[4] Franc BL, Acton PD, Mari C, et al. Small-animal SPECT and SPECT/CT: important tools for preclinical investigation [J]. J Nucl Med, 2008, 49(10): 1651-1663.
[5] Kamiya M. Novel bio-imaging tools based on the precise design of functional fluorescence probes [J]. Yakugaku Zasshi, 2016, 136(10): 1355-1365.
[6] Ntziachristos V, Ripoll J, Wang LV, et al. Looking and listening to light: the evolution of whole-body photonic imaging [J]. Nat Biotechnol, 2005, 23(3): 313-320.
[7] Maggi A, Ciana P. Reporter mice and drug discovery and development [J]. Nat Rev Drug Discov, 2005, 4(3): 249-255.
[8] Zhou J, Yu Z, Zhao S, et al. Lentivirus-based DsRed-2-transfected pancreatic cancer cells for deep in vivo imaging of metastatic disease [J]. J Surg Res, 2009, 157(1): 63-70.
[9] Yang M, Baranov E, Moossa AR, et al. Visualizing gene expression by whole-body fluorescence imaging [J]. Proc Natl Acad Sci U S A, 2000, 97(22): 12278-12282.
[10] Chen X. Visualizing the location and the dynamics of gene expression in living animals through bioluminescence imaging [J]. Methods Cell Biol, 2013, 113: 39-49.
[11] Weissleder R. Scaling down imaging: molecular mapping of cancer in mice [J]. Nat Rev Cancer, 2002, 2(1): 11-18.
[12] Choy G, Choyke P, Libutti SK. Current advances in molecular imaging: noninvasive in vivo bioluminescent and fluorescent optical imaging in cancer research [J]. Mol Imaging, 2003, 2(4): 303-312.
[13] Schaub FX, Reza MS, Flaveny CA, et al. Fluorophore-NanoLuc BRET Reporters enable sensitive in vivo optical imaging and flow cytometry for monitoring tumorigenesis [J]. Cancer Res, 2015, 75(23): 5023-5033.
[14] Ray P. Multimodality molecular imaging of disease progression in living subjects [J]. J Biosci, 2011. 36(3): 499-504.
[15] Lee HW, Gangadaran P, Kalimuthu S, et al. Advances in molecular imaging strategies for in vivo tracking of immune cells [J]. Biomed Res Int, 2016, 2016: 1946585.
[16] Song G, Wu QP, Xu T, et al. Quick preparation of nanoluciferase-based tracers for novel bioluminescent receptor-binding assays of protein hormones: Using erythropoietin as a model [J]. J Photochem Photobiol B, 2015, 153: 311-316.
[17] Awais M, Voronina SG, Sutton R. An efficient method is required to transfect non-dividing cells with genetically encoded optical probes for molecular imaging [J]. Anal Sci, 2015, 31(4): 293-298.
[18] Lee H, Kim YP. Fluorescent and bioluminescent nanoprobes for in vitro and in vivo detection of matrix metalloproteinase activity [J]. BMB Rep, 2015, 48(6): 313-318.
[19] Saytashev I, Glenn R, Murashova GA, et al. Multiphoton excited hemoglobin fluorescence and third harmonic generation for non-invasive microscopy of stored blood [J]. Biomed Opt Express, 2016, 7(9): 3449-3460.
[20] Ma Y, Shaik MA, Kim SH, et al. Wide-field optical mapping of neural activity and brain haemodynamics: considerations and novel approaches [J]. Philos Trans R Soc Lond B Biol Sci, 2016, 371(1705): 20150360.
[21] Lepeltier M, Appaix F, Liao YY, et al. Carbazole-substituted iridium complex as a solid state emitter for two-photon intravital imaging [J]. Inorg Chem, 2016, 55(19): 9586-9595.
[22] Grutzendler J, Gan WB. Two-photon imaging of synaptic plasticity and pathology in the living mouse brain [J]. NeuroRx, 2006, 3(4): 489-496.
[23] Sorbara CD, Wagner NE, Ladwig A, et al. Pervasive axonal transport deficits in multiple sclerosis models [J]. Neuron, 2014, 84(6): 1183-1190.
[24] Theer P, Hasan MT, Denk W. Two-photon imaging to a depth of 1000 microm in living brains by use of a Ti:Al2O3 regenerative amplifier [J]. Opt Lett, 2003, 28(12): 1022-1024.
[25] Zhang P, Jiang XF, Nie X, et al. A two-photon fluorescent sensor revealing drug-induced liver injury via tracking gamma-glutamyltranspeptidase (GGT) level in vivo [J]. Biomaterials, 2016, 80: 46-56.
[26] Sinha S, Liang L, Ho ET, et al. High-speed laser microsurgery of alert fruit flies for fluorescence imaging of neural activity [J]. Proc Natl Acad Sci U S A, 2013, 110(46): 18374-18379.
[27] Greenberg ML, Weinger JG, Matheu MP, et al. Two-photon imaging of remyelination of spinal cord axons by engrafted neural precursor cells in a viral model of multiple sclerosis [J]. Proc Natl Acad Sci U S A, 2014, 111(22): E2349-E2355.
[28] Jiang LW, Wang XF, Wu ZY, et al. Label-free detection of fibrillar collagen deposition associated with vascular elements in glioblastoma multiforme by using multiphoton microscopy [J]. J Microsc, 2017, 265(2): 207-213.
[29] Weinger JG, Greenberg ML, Matheu MP, et al. Two-photon imaging of cellular dynamics in the mouse spinal cord [J]. J Vis Exp, 2015(96): 10.3791/52580.
[30] Alexander NS, Palczewska G, Stremplewski P, et al. Image registration and averaging of low laser power two-photon fluorescence images of mouse retina [J]. Biomed Opt Express, 2016, 7(7): 2671-2691.
[31] Kaspler P, Lazic S, Forward S, et al. A ruthenium(ii) based photosensitizer and transferrin complexes enhance photo-physical properties, cell uptake, and photodynamic therapy safety and efficacy [J]. Photochem Photobiol Sci, 2016, 15(4): 481-495.
[32] Turnbull L, Strauss MP, Liew AT, et al. Super-resolution imaging of the cytokinetic Z ring in live bacteria using fast 3D-structured illumination microscopy (f3D-SIM) [J]. J Vis Exp, 2014(91): 51469.
[33] Oheim M, Michael DJ, Geisbauer M, et al. Principles of two-photon excitation fluorescence microscopy and other nonlinear imaging approaches [J]. Adv Drug Deliv Rev, 2006, 58(7): 788-808.
[34] Niesner R, Andresen V, Neumann J, et al. The power of single and multibeam two-photon microscopy for high-resolution and high-speed deep tissue and intravital imaging [J]. Biophys J, 2007, 93(7): 2519-2529.
[35] Schapper F, Gonçalves JT, Oheim M. Fluorescence imaging with two-photon evanescent wave excitation [J]. Eur Biophys J, 2003, 32(7): 635-643.
[36] Paddock SW. Confocal laser scanning microscopy [J]. Biotechniques, 1999, 27(5): 992-996, 998-1002, 1004.
[37] Alencar H, Funovics MA, Figueiredo J, et al. Colonic adenocarcinomas: near-infrared microcatheter imaging of smart probes for early detection–study in mice [J]. Radiology, 2007, 244(1): 232-238.
[38] Upadhyay R, Sheth RA, Weissleder R, et al. Quantitative real-time catheter-based fluorescence molecular imaging in mice [J]. Radiology, 2007, 245(2): 523-531.
[39] Gee MS, Upadhyay R, Bergquist H, et al. Human breast cancer tumor models: molecular imaging of drug susceptibility and dosing during HER2/neu-targeted therapy [J]. Radiology, 2008, 248(3): 925-935.
[40] Wu X, Chen G, Lu J, et al. Label-free detection of breast masses using multiphoton microscopy [J]. PLoS One, 2013, 8(6): e65933.
[41] Wu X, Chen G, Qiu J, et al. Visualization of basement membranes in normal breast and breast cancer tissues using multiphoton microscopy [J]. Oncol Lett, 2016, 11(6): 3785-3789.
[42] Guse K, Dias JD, Bauerschmitz GJ, et al. Luciferase imaging for evaluation of oncolytic adenovirus replication in vivo [J]. Gene Ther, 2007, 14(11): 902-911.
[43] Hinckley CA, Pfaff SL. Imaging spinal neuron ensembles active during locomotion with genetically encoded calcium indicators [J]. Ann N Y Acad Sci, 2013, 1279: 71-79.
[44] Barbier V, Winkler IG, Wadley R, et al. Flow cytometry measurement of bone marrow perfusion in the mouse and sorting of progenitors and stems cells according to position relative to blood flow in vivo [J]. Methods Mol Biol, 2012, 844: 45-63.
[45] Tao W, Soonpaa MH, Field LJ, et al. Functional screening of intracardiac cell transplants using two-photon fluorescence microscopy [J]. Pediatr Cardiol, 2012, 33(6): 929-937.
[46] Scott MK, Akinduro O, Lo Celso C. In vivo 4-dimensional tracking of hematopoietic stem and progenitor cells in adult mouse calvarial bone marrow [J]. J Vis Exp, 2014(91): e51683.
[47] Koroleva A, Deiwick A, Nguyen A, et al. Osteogenic differentiation of human mesenchymal stem cells in 3-D Zr-Si organic-inorganic scaffolds produced by two-photon polymerization technique [J]. PLoS One, 2015, 10(2): e0118164.
[48] Kandoth N, Kirejev V, Monti S, et al. Two-photon fluorescence imaging and bimodal phototherapy of epidermal cancer cells with biocompatible self-assembled polymer nanoparticles [J]. Biomacromolecules, 2014, 15(5): 1768-1776.
[49] Shimura T, Tanaka K, Toiyama Y, et al. In vivo optical pathology of paclitaxel efficacy on the peritoneal metastatic xenograft model of gastric cancer using two-photon laser scanning microscopy [J]. Gastric Cancer, 2015, 18(1): 109-118.
[50] Zhang Q, Tian X, Hu G, et al. Dual-functional analogous cis-platinum complex with high antitumor activities and two-photon bioimaging [J]. Biochemistry, 2015, 54(13): 2177-2180.
[51] Ma X, Hui H, Shang W, et al. Recent advances in optical molecular imaging and its applications in targeted drug delivery [J]. Curr Drug Targets, 2015, 16(6): 542-548.
[52] Yang G, Pan F, Chang PC, et al. Transcranial two-photon imaging of synaptic structures in the cortex of awake head-restrained mice [J]. Methods Mol Biol, 2013, 1010: 35-43.
[53] Kerschensteiner M, Schwab ME, Lichtman JW, et al. In vivo imaging of axonal degeneration and regeneration in the injured spinal cord [J]. Nat Med, 2005, 11(5): 572-577.
[54] Di Maio A, Skuba A, Himes BT, et al. In vivo imaging of dorsal root regeneration: rapid immobilization and presynaptic differentiation at the CNS/PNS border [J]. J Neurosci, 2011, 31(12): 4569-4582.
[55] Skuba A, Manire MA, Kim H, et al. Time-lapse in vivo imaging of dorsal root nerve regeneration in mice [J]. Methods Mol Biol, 2014, 1162: 219-232.
[56] Zhang Y, Zhang L, Shen J, et al. Two-photon-excited fluorescence microscopy as a tool to investigate the efficacy of methylprednisolone in a mouse spinal cord injury model [J]. Spine (Phila Pa 1976), 2014, 39(8): E493-E499.
[57] Zhang Y, Zhang L, Ji X, et al. Two-photon microscopy as a tool to investigate the therapeutic time window of methylprednisolone in a mouse spinal cord injury model [J]. Restor Neurol Neurosci, 2015, 33(3): 291-300.
[58] Liston C, Gan WB. Glucocorticoids are critical regulators of dendritic spine development and plasticity in vivo [J]. Proc Natl Acad Sci U S A, 2011, 108(38): 16074-16079.
