临床研究

居家运动训练对老年肥胖型肌少症的效果

  • 王丽珍 ,
  • 郭颖彬 ,
  • 骆俊宏
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  • 1. 华侨大学医院,福建泉州市 362021;
    2. 泉州市正骨医院,福建泉州市 362000;
    3. 泉州医学高等专科学校,福建泉州市 362000
王丽珍(1977-),女,汉族,福建泉州市人,主管护师,主要研究方向:老年慢性病康复。

收稿日期: 2018-08-30

  修回日期: 2018-10-22

  网络出版日期: 2019-02-18

Effects of Home Exercise on Sarcopenia Obesity for Aging People

  • WANG Li-zhen ,
  • GUO Ying-bin ,
  • LOU Jiunn-horng
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  • 1. Huaqiao University Hospital, Quanzhou, Fujian 362021, China;
    2. Quanzhou Zhenggu Hospital, Quanzhou, Fujian 362000, China;
    3. Quanzhou Medical College, Quanzhou, Fujian 362000, China

Received date: 2018-08-30

  Revised date: 2018-10-22

  Online published: 2019-02-18

摘要

目的 探讨居家运动训练方式对老年肥胖型肌少症的影响及其机制。
方法 2018年1月至4月,80例老年肥胖型肌少症患者随机分为对照组、渐进式阻力训练(PRT)组、有氧训练(AT)组、肌力和有氧律动训练(CT)组,每组20例。各训练组行预定运动训练,共8周。训练前、训练后8周和训练后12周,检测身体组成、肌力和血液胰岛素样生长因子1 (IGF-1)、白细胞介素6 (IL-6)的变化。
结果 训练后,各训练组骨骼肌质量较对照组增加(P < 0.05),脂肪质量、体质量指数和内脏脂肪面积减少(P < 0.05);各训练组背部肌力升高(P < 0.05),PRT组和CT组握力、膝伸肌力升高(P < 0.05);PRT组和CT组IGF-1升高(P < 0.05),PRT组IL-6下降(P < 0.05)。
结论 居家运动训练能改善老年肥胖型肌少症患者的身体组成,提高肌力,可能与增加IGF-1分泌、降低IL-6浓度有关。

本文引用格式

王丽珍 , 郭颖彬 , 骆俊宏 . 居家运动训练对老年肥胖型肌少症的效果[J]. 中国康复理论与实践, 2019 , 25(1) : 90 -96 . DOI: 10.3969/j.issn.1006-9771.2019.01.012

Abstract

Objective To explore the effects of home exercise on sarcopenia obesity elderly.
Methods From January to April, 2018, 80 patients with sarcopenia obesity were randomly divided into control group (CONG, n = 20), progressive resistance training group (PRTG, n = 20), aerobic exercise training group (ATG, n = 20) and muscle strength combined with aerobic exercise training group (CTG, n = 20). The training groups accepted their exercise in home for eight weeks. Their body composition, muscle strength, and insulin-like growth factor 1 (IGF-1) and interleukin 6 (IL-6) in blood were measured before training, eight weeks and twelve weeks after training.
Results Skeletal muscle mass increased in all the training groups compared with that of CONG after training, while fat mass, body mass index and visceral fat area reduced. Muscle strength increased in all the training groups compared with that of CONG after training, while the grip strength, knee extensor strength increased in PRTG and ATG. IGF-1 increased in PRTG and ATG, while IL-6 decreased in PRTG.
Conclusion Home exercise can improve the body composition of patients with sarcopenia obesity elderly, as well as muscle strength, which may be related to increase of IGF-1 and decrease of IL-6.

参考文献

[1] Kwon Y N, Yoon S S, Lee K H.Sarcopenic obesity in elderly Korean women: a nationwide cross-sectional study[J]. J Bone Metab, 2018, 25(1): 53-58.
[2] Cruz-Jentoft A J, Baeyens J P, Bauer J M, et al. Sarcopenia: European congsensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People[J]. Age Ageing, 2010, 39(4): 412-423.
[3] 杨鹏,孙丽红,韩雪晶,等. 基于灰色关联分析的老年人下肢肌力手持式肌力测试仪评估[J]. 中国康复理论与实践, 2017, 23(10): 1203-1208.
[4] 张冰,李维辛. 老年人糖尿病相关性肌少症的研究进展[J]. 中国康复理论与实践, 2016, 22(11): 1294-1297.
[5] Verlaan S, Aspray T J, Bauer J M, et al.Nutritional status, body composition, and quality of life in community-dwelling sarcopenic and non-sarcopenic older adults: a case-control study[J]. Clin Nutr, 2017, 36(1): 267-274.
[6] Studenski S A, Peters K W, Alley D E, et al.The FNIH sarcopenia project: rationale, study description, conference recommendations, and final estimates[J]. J Gerontol A Biol Sci Med Sci, 2014, 69(5): 547-558.
[7] Wagenmakers E J, Verhagen J, Ly A, et al.A power fallacy[J]. Behav Res Methods, 2015, 47(4): 913-917.
[8] Kalanka P J, Hon K T.Analysis of means approach for random factor analysis[J]. J Appl Stat, 2018, 45(8): 1426-1446.
[9] American College of Sports Medicine. Appropriate physical activity intervention strategies for weight loss and prevention of weight regain for adults, position stand[J]. Med Sci Sports Exerc, 2009, 41(2): 459-471.
[10] Harsh P, Hassan A, Raef M, et al.Aerobic vs anaerobic exercise training effects on the cardiovascular system[J]. World J Cardiol, 2017, 9(2): 134-138.
[11] Menant J C, Weber F, Lo J, et al.Strength measures are better than muscle mass measures in predicting health-related outcomes in older people: time to abandon the term sarcopenia?[J]. Osteoporos Int, 2017, 28(1): 59-70.
[12] Flegal K M, Kruszon-Moran D, Carroll M D, et al.Trends in obesity among adults in the United States, 2005 to 2014[J]. JAMA, 2016, 315(21): 2284-2291.
[13] Chiu S C, Yang R S, Yang R J, et al.Effects of resistance training on body composition and functional capacity among sarcopenic obese residents in long-term care facilities: a preliminary study[J]. BMC Geriatr, 2018, 18(1): 21.
[14] Barazzoni R, Bischoff S, Boirie Y, et al.Sarcopenic obesity: time to meet the challenge[J]. Obes Facts, 2018, 11(4): 294-305.
[15] Öztürk Z A, Türkbeyler İ H, Abiyev A, et al.Health-related quality of life and fall risk associated with age-related body composition changes; sarcopenia, obesity and sarcopenic obesity[J]. Intern Med J, 2018, 48(8): 973-981.
[16] Musumeci G.Sarcopenia and exercise “The State of the Art”[J]. J Funct Morphol Kinesiol, 2017, 2(40): 1-11.
[17] Vlietstra L, Hendrickx W, Waters D L.Exercise interventions in healthy older adults with sarcopenia: a systematic review and meta-analysis[J]. Australas J Ageing, 2018, 37(3):169-183.
[18] Huang S W, Ku J W, Lin L F, et al.Body composition influenced by progressive elastic band resistance exercise of sarcopenic obesity elderly women: a pilot randomized controlled trial[J]. Eur J Phys Rehabil Med, 2017, 53(4): 556-563.
[19] Vascongcelos K S, Dias J M, Araújo M C, et al.Effects of a progressive resistance exercise program with high-speed component on the physical function of older women with sarcopenic obesity: a randomized controlled trial[J]. Braz J Phys Ther, 2016, 20(5): 432-440.
[20] Beaudart C, Dawson A, Shaw S C, et al.Nutrition and physical activity in the prevention and treatment of sarcopenia: systematic review[J]. Osteoporos Int, 2017, 28(6): 1817-1833.
[21] Kemmler W, Teschler M, Weißenfels A, et al.Prevalence of sarcopenia and sarcopenic obesity in older German men using recognized definitions: high accordance but low overlap[J]. Osteoporos Int, 2017, 28(6): 1881-1891.
[22] Batsis J A, Villareal D T.Sarcopenic obesity in older adults: aetiology, epidemiology and treatment strategies[J]. Nat Rev Endocrinol, 2018, 14(9): 513-537.
[23] Ethgen O, Beaudart C, Buckinx F, et al.The future prevalence of sarcopenia in Europe: a claim for public health action[J]. Calcif Tissue Int, 2017, 100(3): 229-234.
[24] Kim J C, Kang Y S, Noh E B, et al.Congcurrent treatment with ursolic acid and low-intensity treadmill exercise improves muscle atrophy and related outcomes in rats[J]. Korean J Physiol Pharmacol, 2018, 22(4): 427-436.
[25] Bischoff-Ferrari H A, Orav J E, Kanis J A, et al. Comparative performance of current definitions of sarcopenia against the prospective incidence of falls among community-dwelling seniors age 65 and older[J]. Osteoporos Int, 2015, 26(12): 2793-2802.
[26] Dutra M T, Gadelha A B, Nóbrega O T, et al.Body Adiposity index, but not visceral adiposity index, correlates with inflammatory markers in sarcopenic obese elderly women[J]. Exp Aging Res, 2017, 43(3): 291-304.
[27] Springer J, Springer J I, Anker S D.Muscle wasting and sarcopenia in heart failure and beyond: update 2017[J]. ESC Heart Fail, 2017, 4(4): 492-498.
[28] Lacroix A, Hortobágyi T, Beurskens R, et al.Effects of supervised vs. unsupervised training programs on balance and muscle strength in older adults: a systematic review and meta-analysis[J]. Sports Med, 2017, 47(11): 2341-2361.
[29] Churilov I, Churilov L, MacIsaac R J, et al. Systematic review and meta-analysis of prevalence of sarcopenia in post acute inpatient rehabilitation[J]. Osteoporos Int, 2018, 29(4): 805-812.
[30] Giovanni I, Gioconda D, Francesca G, et al.Physical exercise and sarcopenia in older people: position paper of the Italian Society of Orthopaedics and Medicine[J]. Clin Cases Miner Bone Metab, 2014, 11(3): 215-221.
[31] Brown J C, Harhay M O, Harhay M N.Sarcopenia and mortality among a population-based sample of community-dwelling older adults[J]. J Cachexia Sarcopenia Muscle, 2016, 7(3): 290-298.
[32] Marc F, Bénédicte D, Damien N, et al.Aging reduces the activation of the mTORC1 pathway after resistance exercise and protein intake in human skeletal muscle: potential role of REDD1 and impaired anabolic sensitivity[J]. Nutrients, 2016, 8(1): 47.
[33] Rygiel K A, Picard M, Turnbull D M.The ageing neuromuscular system and sarcopenia: a mitochondrial perspective[J]. J Physiol, 2016, 594(16): 4499-4512.
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