《Chinese Journal of Rehabilitation Theory and Practice》 ›› 2019, Vol. 25 ›› Issue (3): 314-318.doi: 10.3969/j.issn.1006-9771.2018.00.014

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Advance in Electroencephalographic and Imaging Studies in Depression Children and Adolescents (review)

AN Wen-jun1, LI Jin-hua2, WANG He-ping2   

  1. 1.School of Education Science, Guizhou Education University, Guiyang, Guizhou 550018, China
    2.Special Education, Faculty of Education, East China Normal University, Shanghai 200062, China
  • Received:2018-06-13 Revised:2018-10-09 Published:2019-03-25 Online:2019-04-02
  • Contact: WANG He-ping, E-mail: hpwang@spe.ecnu.edu.cn

Abstract: tudies with electroencephalography, transcranial Doppler (TCD), magnetic resonance, positron emission tomography (PET), and single-photon emission computed tomography (SPECT) have achieved some positive results for depression in children and adolescents. Electroencephalographic studies found that the patients' α, β, δ, θ waves, and P300, P200, N100 and N200 in event-related potential (ERP) were significantly different from typical ones, and cortical activation area was uneven. TCD, magnetic resonance, PET and SPECT studies found that the patients with depression occurred cerebral blood flow abnormalities in frontal lobe and temporal lobe. Magnetic resonance studies found that there were brain structural and metabolic abnormalities in frontal lobe, left fusiform gyrus and anterior cingulate cortex, and N-acetyl aspartate, creatine, choline and glutamate might be a part of the cause of depression.

Key words: children, adolescents, depression, electroencephalography, imaging, review

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