《中国康复理论与实践》

《中国康复理论与实践》 ›› 2019, Vol. 25 ›› Issue (3): 279-283.doi: 10.3969/j.issn.1006-9771.2019.03.006

• 专题 • 上一篇    下一篇

中老年脑卒中患者握力与认知功能的关系探讨：来自中国健康与退休前瞻性队列研究

张伟1,2, 张通1,2   

  1. 1.中国康复研究中心北京博爱医院神经康复中心，北京市 100068
    2.首都医科大学康复医学院，北京市 100068
  • 收稿日期:2018-09-17 修回日期:2018-11-27 出版日期:2019-03-25 发布日期:2019-04-02
  • 通讯作者: 张伟,E-mail: 69818091@qq.com
  • 作者简介:张伟(1977-)，女，汉族，北京市人，博士，主治医师，主要研究方向：神经病学、神经康复学及睡眠医学。

Association between Grip Strength and Cognitive Function among Middle-aged and Older Adults with Stroke: Findings from the China Health and Retirement Longitudinal Study

ZHANG Wei1,2, ZHANG Tong1,2   

  1. 1.Neurorehabilitation Centre, Beijing Bo’ai Hospital, China Rehabilitation Research Centre, Beijing 100068, China
    2.Capital Medical University School of Rehabilitation Medicine, Beijing100068, China
  • Received:2018-09-17 Revised:2018-11-27 Published:2019-03-25 Online:2019-04-02
  • Contact: ZHANG Wei, E-mail: 69818091@qq.com

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摘要： 目的 本研究旨在评估握力与认知功能在中老年脑卒中患者中的关系。方法 本研究采用中国健康与退休前瞻性队列研究(CHARLS)中412例脑卒中患者2011年至2012年的基线调查数据，分析脑卒中患者握力与认知功能的关系以及性别的影响。结果 握力可增加认知功能得分。每增加5 kg握力，脑卒中患者能够正确画出图案的概率增加30%(95%CI: 8%~57%, P = 0.005)。同时，情节记忆增加0.15分(P = 0.003)，电话筛查认知功能增加0.30分(P = 0.001)，总认知得分增加0.60分(P < 0.001)。握力与所有认知指标的关系在女性脑卒中患者中更强，尤其是情节记忆得分方面具有性别差异(P = 0.049)。结论 握力与认知能力的各项指标均呈正相关。握力对认知功能的作用在女性脑卒中患者中的作用更大。

关键词: 脑卒中, 握力, 认知功能, 性别差异

Abstract: Objective To explore the relationship between grips strength and cognitive function among stroke patients in China. Methods The data of 412 post-stroke participants from the baseline survey of the China Health and Retirement Longitudinal Study (CHARLS) were selected. The association between grip strength and cognitive function was analyzed, especially in gender. Results Grip strength was positively associated with all cognitive measures. For every 5 kg increase in grip strength, the likelihood increased 30% in correctly drawing picture (95%CI: 8%-57%, P = 0.005); and the scores increased 0.15 points in episodic memory (P = 0.003), 0.30 points in Telephone Interview of Cognitive Status (TICS-10) (P = 0.001), and 0.60 points (P < 0.001) in the overall cognition scores. The association between grip strength and cognitive measures was stronger among female patients, particularly for episodic memory (P = 0.049). Conclusion Grip strength was positively associated with cognitive function among stroke patients. The association was stronger among female patients.

Key words: stroke, grip strength, cognitive function, gender difference

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