《中国康复理论与实践》 ›› 2019, Vol. 25 ›› Issue (5): 546-549.doi: 10.3969/j.issn.1006-9771.2019.05.008

• 综述 • 上一篇    下一篇

弥散张量成像在脑卒中患者运动功能预后评估中的研究进展

谢运娟1, 廖伶艺1, 高强1,2   

  1. 1.四川大学,四川成都市 610041
    2.四川大学华西医院康复医学中心,四川成都市 610041
  • 收稿日期:2019-02-22 修回日期:2019-03-22 出版日期:2019-05-25 发布日期:2019-05-29
  • 通讯作者: 高强(1982-),男,汉族,博士,副教授,主要研究方向:神经康复。E-mail: gaoqiang_hxkf@163.com
  • 作者简介:谢运娟(1996-),女,汉族,广东梅州市人,硕士研究生,主要研究方向:神经康复。
  • 基金资助:
    四川省科技厅重点研发项目(No. 2018FZ0103)

Advance in Diffusion Tensor Imaging for Predicting Motor Function Outcome after Stroke

XIE Yun-juan1, LIAO Ling-yi1, GAO Qiang1,2   

  1. 1.Sichuan University, Chengdu, Sichuan 610041, China
    2.Rehabilitation Medicine Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China
  • Received:2019-02-22 Revised:2019-03-22 Published:2019-05-25 Online:2019-05-29
  • Contact: GAO Qiang, E-mail: gaoqiang_hxkf@163.com
  • Supported by:
    Sichuan Science and Technology Department Key Research and Development Projects (No. 2018FZ0103)

摘要: 弥散张量成像可表征水分子扩散过程的取向特性,能有效观察和追踪脑白质纤维束。脑卒中患者各向异性分数下降表明纤维结构完整性受损,显著下降提示可能出现华勒变性;各向异性分数升高与运动功能恢复程度有关;患健侧各向异性分数比更适合成为脑卒中患者运动功能恢复预测指标。纤维束成像显示的皮质脊髓束变化,也可作为脑卒中患者运动功能结局的预测指标。

关键词: 脑卒中, 弥散张量成像, 运动功能, 预后, 综述

Abstract: Diffusion tensor imaging (DTI) can be used to characterize the orientation of water diffusion, and track white matter fiber bundles. The decrease of fractional anisotropy after stroke indicates impairment of structural integrity of fibers, even Wallerian degeneration if serious; in another hand, the increase of fractional anisotropy relates to the more recovery of motor function. The affected/unaffected ratios of fractional anisotropy are more suitable for predicting motor function recovery after stroke. The changes of corticospinal tract in diffusion tensor tractography can also predict the motor outcome in stroke patients.

Key words: stroke, diffusion tensor imaging, motor function, prognosis, review

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