Abstract: ObjectiveTo summarize experience of surgical treatment of severe acute pancreatitis (SAP) and find out suitable treatment program.MethodsThe data of 52 SAP cases treated from 1990 to 2005 were analyzed retrospectively.ResultsThe mortality rate of 20 cases received operation at early stage was 35% (7/20) and the incidence rates of complications such as adult respiratory distress syndrome (ARDS), shock, renal failure and cardiac failure were 25% (5/20), 35% (7/20), 20% (4/20) and 45% (9/20) respectively. While, the mortality rate of 32 cases received non-surgical treatment at early stage and operation in the later stage was 15.63% (5/32), and incidence rates of ARDS, shock, renal failure and cardiac failure were 6.25% (2/32), 12.5% (4/32), 12.5% (4/32) and 15.63% (5/32) respectively. There was a significant difference between two groups (P<0.05).ConclusionIntegrated treatment that non-surgical procedures at early stage combined with operation in the later stage can effectively decrease mortality rate and complications.

Key words: severe acute pancreatitis, surgical treatment, complication