脑缺血后周细胞及相关血管生成信号通路的研究进展

doi:10.3969/j.issn.1006-9771.2019.00.002

Abstract

Abstract: Pericytes, endothelial cells (EC), astrocytes and extracellular space together constitute the blood-brain barrier. Pericytes and EC participate in the various regulations of blood-brain barriers through many mechanisms to maintain the stability of neurovascular units (NVU). The injury and repair of NVU involve a lot of signal transduction at molecular levels, and angiogenesis is primarily about the generation and maturation of EC and the supporting adhesion process of pericytes. This article briefly reviewed EC-related angiogenesis signaling pathways in pericytes after NVU ischemic injury.

Key words: cerebral ischemia, pericytes, endothelial cell, angiogenesis, neurovascular unit

CLC Number:

R743.3

ZHANG Di, XU Ming-shu, ZHANG Ying-jie, CHENG Ai-fang, GUAN Hua-zong. Advance in Pericytes and Related Angiogenic Signaling Pathways after Cerebral Ischemia (review)[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2019, 25(5): 534-539.

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Advance in Pericytes and Related Angiogenic Signaling Pathways after Cerebral Ischemia (review)

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