《Chinese Journal of Rehabilitation Theory and Practice》 ›› 2019, Vol. 25 ›› Issue (7): 805-812.doi: 10.3969/j.issn.1006-9771.2019.07.013

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Advance in Aromatase Inhibitor Related Arthralgias (review)

ZHONG Jiu-gen1, HOU Xiao-hui1,2, LAN Hao2   

  1. 1.School of Kinesiology, Shanghai University of Sport, Shanghai 200438, China
    2.Guangzhou Sport University, Guangzhou, Guangdong 510000, China
  • Received:2019-01-02 Revised:2019-03-04 Published:2019-07-25 Online:2019-07-23
  • Contact: HOU Xiao-hui E-mail:147077302@qq.com
  • Supported by:
    Supported by Guangdong Science and Technology Projects (Major) (No. 20130325C) and Department of Education of Guangdong International Cooperation Project (Major) (No. 2014WGJHZ005)

Abstract: Estrogen deficiency, inflammatory reactions, metabolic disorders, etc., are considered to be possible mechanisms leading to arthralgias (or joint pain) associated with aromatase inhibitors (AIs) in breast cancer patients. The use of exercise and other non-pharmacological means (such as vitamin D, Omega-3 fatty acids, acupuncture, etc.) may relieve AIs-related arthralgia, and exercise may play a direct or indirect role to deal with the related pathogenesis. But the results of the studies are still controversial.

Key words: breast cancer, aromatase inhibitors, arthralgia, exercise, review

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