丰富康复训练对脑卒中患者认知功能和血清精氨酸的影响

doi:10.3969/j.issn.1006-9771.2019.10.011

Abstract

Abstract: Objective To observe the effects of enriched rehabilitation on cognitive function and serum arginine in stroke patients. Methods From January, 2017 to June, 2018, 40 patients in our department were randomly divided into conventional group (n = 20) and enriched group (n = 20). The conventional group received cognitive rehabilitation, and the enriched group received enriched rehabilitation, once a day, six times a week for three months. Before treatment and three months after treatment, the cognitive function was assessed with Montreal Cognitive Assessment (MoCA), Digit Span Test and Stroop Color Word Test, and the levels of serum arginine and malondialdehyde were detected. Results Finally, all the patients completed the experiment. There was no significant difference in the scores of MoCA, Digit Span Test and Stroop Color Word Test, and the level of serum arginine and malondialdehyde before treatment (t < 1.243, P > 0.05). Three months after treatment, all the above indexes improved (t > 2.170, P < 0.05), and were better in the enriched group than in the conventional group (t > 2.278, P < 0.05). Conclusion Enriched rehabilitation could improve the cognitive function of patients after stroke, which might be related to the significant reduction of the elevated serum arginine and reduction of oxidative damage after stroke.

Key words: stroke, enriched rehabilitation, cognitive dysfunction, arginine, oxidative damage

CLC Number:

R743.3

WANG Xin, ZHOU Hong-yu, JIN Xing, XU Chi, LIN Chun, LIU Jia-yu, WU Shu-hua. Effects of Enriched Rehabilitation on Cognitive Function and Serum Arginine in Stroke Patients[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2019, 25(10): 1177-1182.

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Effects of Enriched Rehabilitation on Cognitive Function and Serum Arginine in Stroke Patients

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