重度脑外伤患者长期功能结局的影响因素

doi:10.3969/j.issn.1006-9771.2020.09.016

Abstract

Abstract:

Objectives To investigate the factors related to the long-term outcome for patients after severe traumatic brain injury.
Methods From January, 2015 to December, 2018, 135 patients with severe traumatic brain injury were selected. Their gender, age (of onset), education level, injury sites, and lesion side were recorded, and they were assessed with Disability Rating Scale (DRS), Mini-Mental State Examination (MMSE), Fugl-Meyer Assessment (FMA) for motor and balance and modified Barthel Index (MBI). They were assessed with DRS again one year after discharge.
Results The age (r = 0.188), early DRS score (r = 0.530), MMSE score (r = -0.376), FMA for motor (r = -0.284) and balance (r = -0.425) score, MBI score (r = -0.480), brain stem injury (r = 0.194) and diffuse brain injury (r = 0.202) were related to DRS scores as follow-up (P < 0.05); while, the gender ( r = -0.175), early DRS score (r = 0.586), MMSE score (r = -0.242), FMA for motor (r = -0.301) and balance (r = -0.228) score, MBI score (r = -0.367) and occipital lobe injury (r = 0.209) were related to difference of DRS (P < 0.05).
Conclusion The age, early cognitive and motor dysfunction are related with the outcome of one year of patients after severe traumatic brain injury. More researches are needed to explore the impact of injury sites on the outcome.

Key words: traumatic brain injury, Disability Rating Scale, related factors, outcome

ZHANG Xin,ZHANG Xiao-nian,SUN Xin-ting,CHI Qian-qian. Influence Factors Related to Long-term Outcome for Patients with Severe Traumatic Brain Injury[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2020, 26(9): 1089-1092.

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References 19

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变量	变量值	赋值	变量	变量值	赋值
性别(n)			累及部位(n)		是 = 1,否 = 0
男	108	1	额叶	77
女	27	0	颞叶	86
发病年龄(岁)	34.63±15.79	数值变量	顶叶	58
教育年限(年)	11.52±4.14	数值变量	枕叶	32
昏迷时间(d)	28.38±57.69	数值变量	基底节	25
损伤侧(n)		是 = 1,否 = 0	脑干	18
左侧	50		小脑	6
右侧	45		弥散性损害	8
双侧	40		初次DRS评分	11.49±6.59	数值变量
FMA运动评分	58.49±31.17	数值变量	随访时DRS评分	6.88±5.55	数值变量
FMA平衡评分	6.74±4.88	数值变量	MMSE评分	19.10±8.52	数值变量
MBI评分	45.62±30.82	数值变量

自变量	r值	P值	自变量	r值	P值
性别	0.056	0.517	损伤累及部位
发病年龄	0.188	0.029	额叶	-0.033	0.705
教育年限	-0.120	0.174	颞叶	-0.108	0.216
昏迷时间	0.171	0.055	顶叶	-0.081	0.352
受伤侧			枕叶	-0.089	0.307
左侧	-0.065	0.452	基底节	-0.020	0.819
右侧	-0.148	0.088	脑干	0.194	0.025
双侧	0.155	0.074	小脑	0.002	0.981
FMA运动评分	-0.284	0.001	弥散性损害	0.202	0.020
FMA平衡评分	-0.425	< 0.001	初次DRS评分	0.530	< 0.001
MBI评分	-0.480	< 0.001	MMSE评分	-0.376	< 0.001

自变量	r值	P值	自变量	r值	P值
性别	-0.175	0.043	损伤累及部位
发病年龄	-0.027	0.752	额叶	0.077	0.377
教育年限	0.039	0.659	颞叶	0.063	0.467
昏迷时间	0.161	0.071	顶叶	0.094	0.280
受伤侧			枕叶	0.209	0.016
左侧	-0.045	0.605	基底节	0.054	0.534
右侧	-0.063	0.473	脑干	-0.090	0.305
双侧	0.034	0.693	小脑	-0.029	0.739
FMA运动评分	-0.301	0.007	弥散性损害	0.130	0.136
FMA平衡评分	-0.228	0.010	初次DRS评分	0.586	< 0.001
MBI评分	-0.367	< 0.001	MMSE评分	-0.242	0.013

Influence Factors Related to Long-term Outcome for Patients with Severe Traumatic Brain Injury

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