细胞生长因子在神经康复与神经可塑性中的研究进展

doi:10.3969/j.issn.1006-9771.2021.00.005

Abstract

Abstract:

With potent biological activities, cellular growth factors are polypeptide factors that primarily stimulate cell growth and proliferation. They participate in the regulation of not only normal physiological functions such as human embryonic development and cell growth, but also neurorehabilitation and neuroplasticity in pathological processes such as nerve injury and recovery. Specifically, cellular growth factors have been shown to promote neuron survival, facilitate nerve regeneration and regulate synaptic plasticity, promote cell differentiation/vascular regeneration and modulate the microenvironment, promote nerve fiber myelination and improve nerve conduction. This review summarized current knowledge on the roles and various growth factors in neurorehabilitation and neuroplasticity, providing an update on potential clinical application of cellular growth factors in the field of neural rehabilitation.

Key words: cellular growth factors, neurorehabilitation, neuroplasticity, review

CLC Number:

R741

LI Xiaokun,LIU Xu,LIU Jianhua,RAO Zhiheng,Yongde LUO,CHEN Keyang,ZHANG Tong. Progress of cellular growth factors in neurorehabilitation and neuroplasticity[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2022, 28(2): 175-182.

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Progress of cellular growth factors in neurorehabilitation and neuroplasticity

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