体力活动水平对帕金森病发病风险的影响：基于CHARLS数据的横断面分析

doi:10.3969/j.issn.1006-9771.2023.10.003

Abstract

Abstract:

Objective To investigate the effect of different levels of physical activity on the risk of Parkinson's disease (PD).
Methods A total of 9 726 subjects from 2018 China Health and Retirement Longitudinal Study (CHARLS) data were analyzed with multivariate Logistic regression analysis.
Results Of the 9 726 subjects, 188 suffered from PD, with a prevalence of 1.93%. The subjects who aged more than 65 (OR = 2.58, 95%CI 1.74 to 3.96, P < 0.001) and widowed (OR = 1.42, 95%CI 1.01 to 1.99, P = 0.043) were at a higher risk of developing PD. Subjects who engaged in high-intensity physical activities (OR = 0.38, 95%CI 0.27 to 0.54, P < 0.001) were at a lower risk of PD. After adjusting for age and marital status, high-intensity physical activity still reduced the risk of PD (OR = 0.42, 95%CI 0.29 to 0.61, P < 0.001).
Conclusion High-intensity physical activity (over 3 000 metabolic equivalents a week) may reduce the risk of PD.

Key words: Parkinson's disease, middle-aged, elderly, risk, physical activity

CLC Number:

R742.5

WU Jiayu, MENG Detao, LIANG Xiaoxiao. Effect of physical activity levels on risk of Parkinson's disease: a cross-sectional analysis based on China Health and Retirement Longitudinal Study[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2023, 29(10): 1135-1139.

Figures/Tables 3

References 34

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项目		非帕金森病(n = 9538)	帕金森病(n = 188)	χ²值	P值
年龄	< 65岁	2924	27	22.857	< 0.001
	≥ 65岁	6431	156
性别	女	4879	94	0.098	0.754
	男	4659	94
受教育程度	小学以下	7172	148	2.393	0.495
	初中	1465	27
	高中	537	6
	大学及以上	364	7
婚姻状态	已婚	7316	134	6.783	0.148
	分居	318	5
	离异	79	3
	丧偶	1770	46
	单身	55	0
居住地	城镇	2241	45	0.016	0.900
	农村	7277	143
民族	其他民族	675	15	0.227	0.633
	汉族	8863	173
体力活动水平	低强度	1899	62	27.935	< 0.001
	中强度	2587	63
	高强度	5052	63

项目	OR	95% CI	P值
年龄
< 65岁	1.00
≥ 65岁	2.58	1.74~3.96	< 0.001
性别
女	1.00
男	1.05	0.79~1.40	0.754
受教育程度
小学以下	1.00
初中	0.88	0.59~1.35	0.593
高中	0.53	0.24~1.23	0.143
大学及以上	0.93	0.43~2.00	0.857
婚姻状态
已婚	1.00
分居	0.86	0.35~2.11	0.740
离异	2.07	0.65~6.65	0.220
丧偶	1.42	1.01~1.99	0.043
单身	0.00	0.00	0.997
居住地
城镇	1.00
农村	0.98	0.70~1.37	0.981
民族
其他民族	1.00
汉族	0.88	0.52~1.50	0.634
体力活动水平
低强度	1.00
中强度	0.75	0.52~1.06	0.106
高强度	0.38	0.27~0.54	< 0.001

体力活动水平	调整前			调整后
体力活动水平	OR	95%CI	P值	OR	95%CI	P值
低强度	1.00			1.00
中强度	0.75	0.52~1.06	0.106	0.79	0.55~1.13	0.324
高强度	0.38	0.27~0.54	< 0.001	0.42	0.29~0.61	< 0.001

Effect of physical activity levels on risk of Parkinson's disease: a cross-sectional analysis based on China Health and Retirement Longitudinal Study

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