卒中后失语工作记忆的事件相关电位及时频特征

doi:10.3969/j.issn.1006-9771.2024.03.009

Abstract

Abstract:

Objective To explore the task-state electroencephalogram (EEG) characteristics of working memory in patients with post-stroke aphasia (PSA).

Methods From September, 2020 to February, 2021, a total of eight patients with PSA (PSA group) and eight healthy adults (HC group) were recruited to collect EEG and memory scale data. The EEG data of working memory task-states were used to analyze the characteristics of the EEG frequency band indicators in time domain event-related potentials (ERP) and frequency; and the correlation with the items in the memory scale.

Results Finally, five patients and five controls were included. N1 and P2 components were induced in the frontal area, and P300 components were induced in the parieto-occipital area. Compared with HC group, the activation of N1 and P2 increased in central prefrontal region, while the activity of P300 decreased in the right parieto-occipital region in PSA group (|t| > 2.193, P < 0.05). The energy of theta band decreased in the right prefrontal region and the central parieto-occipital region, the energy of alpha1 band decreased in the left parieto-occipital region, and the energy of gamma band increased in the left central region (t > 2.398, P < 0.05). The energy of gamma band correlated with immediate recall (r = 0.914, P = 0.030) and correct recognition (r = 0.931, P = 0.022) of Auditory Verbal Learning Test, and inverting (r = 0.924, P = 0.025) and anterograde (r = 0.889, P = 0.044) of Digit Span Test.

Conclusion Visual working memory task can activate the compensatory processing activity of memory related brain regions after PSA, which can be used as an objective indication for the evaluation of PSA working memory related research. There is close relationship between language impairment and working memory.

Key words: post-stroke aphasia, working memory, electroencephalography, event-related potentials, visual working memory task, characteristics

CLC Number:

R743.3

HUANG Xing, CHANG Jingling, ZHANG Zihan, LI Ying. Characteristics of event-related potential and frequency on working memory of post-stroke aphasia[J]. Chinese Journal of Rehabilitation Theory and Practice, 2024, 30(3): 316-325.

Figures/Tables 8

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References 42

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组别	n	年龄/岁	受教育年限/年
HC组	5	55.20±17.24	13.00±3.00
PSA组	5	68.60±12.44	10.40±3.13
t值		0.196	-1.341
P值		0.644	0.217

分项	评分
即刻回忆	9.60±5.59
短延迟回忆	1.60±1.14
长延迟回忆	0.40±0.55
延迟回忆总分	2.00±1.22
正确再认	7.40±4.56
正确否认	7.00±4.06
再认总分	14.40±8.56
顺背	7.40±5.50
倒背	2.00±1.58

Characteristics of event-related potential and frequency on working memory of post-stroke aphasia

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