完全性脊髓损伤后血清S-100β 蛋白浓度的变化①

doi:10.3969/j.issn.1006-9771.2016.07.019

Abstract

Abstract: Objective To evaluate whether S-100β protein could be a serum marker for traumatic spinal cord injury (SCI). Methods From June, 2013 to October, 2014, 24 patients with complete SCI were measured the serum S- 100β protein concentrations with enzyme- linked immunosorbent assay, one week, three and six months after SCI. Serum from ten healthy persons was as normal control. Results The serum S-100β protein concentrations increased one week and 3 months after SCI (Z>4.273, P<0.001). Conclusion The increase of serum S-100β protein may help assessing early impairment after complete SCI.

Key words: spinal cord injury, S-100&beta, protein, serum, biomarker

WANG Yu- ming1,2, ZHU Zhi- min3, CHE Jun- yan1,2, LI Hui- lan1,2, MA Ke1,2, GONG Hui- ming1,2, CHEN Hui1,2, ZHONG Hua3, YANG Ming-liang1,2, DU Liang-jie1,2. Changes of Serum S-100β Protein after Complete Spinal Cord Injury[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, doi: 10.3969/j.issn.1006-9771.2016.07.019.

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Changes of Serum S-100β Protein after Complete Spinal Cord Injury

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