《Chinese Journal of Rehabilitation Theory and Practice》 ›› 2016, Vol. 22 ›› Issue (12): 1420-1419.doi: 10.3969/j.issn.1006-9771.2016.12.012

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Research Progress of Ozone Oxidation and Ischemia-reperfusion Injury (review)

TAO Xi, HUANG Liang, CAI Hua-an, DENG Jing-gui   

  1. People's Hospital of Hunan Province, Changsha, Hunan 410016, China
  • Received:2016-07-30 Published:2016-12-25 Online:2017-01-15
  • Contact: CAI Hua-an. E-mail: 623124733@qq.com

Abstract: As an active oxygen, ozone can induce oxidative stress, however, small doses of ozone pretreatment of the body may develop to oxidation toleration, even anti-oxidative damage, thereby protecting organ from ischemia-reperfusion injury. This paper reviewed the status of ozone pretreatment in organ ischemia-reperfusion, such as heart, kidney, liver, skeletal muscle, gonads and brain. Ozone therapy may have potential application values in organ transplants and cardiovascular diseases. Meanwhile, whether clinical application of ozone big autohemotherapy in ischemic cerebrovascular disease is reasonable or not in nearly 10 years was put forward.

Key words: ozone oxidation, ischemia-reperfusion injury, ischemic cerebrovascular disease, review

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