《Chinese Journal of Rehabilitation Theory and Practice》 ›› 2017, Vol. 23 ›› Issue (5): 553-557.doi: 10.3969/j.issn.1006-9771.2017.05.013

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Advances of Molecular Mechanisms on Obesity Inducing Muscle Atrophy (review)

LUO Lin1,2, YANG Jin-peng3, WANG Song-tao4, LIAO Xin5, ZHAN Wei5   

  1. 1. Guizhou Normal University, Guiyang, Guizhou 550001, China;
    2. Beijing Sport University, Beijing 100084, China;
    3. The PLA Information Engineering University, Zhengzhou, Henan 450001, China;
    4. South China Normal University, Guangzhou, Gguangdong 510006, China;
    5. The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou 550001, China
  • Received:2016-12-09 Revised:2017-01-16 Published:2017-05-25 Online:2017-05-24
  • Contact: LUO Lin. E-mail: 5925860@qq.com

Abstract: Obesity is becoming a chronic epidemic worldwide. Persistent obesity, in addition to triggering changes in skeletal muscle function and structure, may also lead to the occurrence of skeletal muscle atrophy, that maybe associate with autophagy and ubiquitin proteasome, interleukin-6, leptin, adiponectin, interleukin-10, tumor necrosis factor-alpha, growth hormone, angiotensin II, glucocorticoid, advanced glycation end-product and myostatin, etc.

Key words: obesity, muscle atrophy, signal pathway, review

CLC Number: