《Chinese Journal of Rehabilitation Theory and Practice》 ›› 2017, Vol. 23 ›› Issue (10): 1152-1156.doi: 10.3969/j.issn.1006-9771.2017.10.006

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Advance of microRNAs for Spine Cord Injury (review)

ZHANG Zheng-pei, YU Ling, SUN Xiang-ran, GUO Wei-chun   

  1. Department of Orthopedics, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, China
  • Received:2017-03-13 Revised:2017-04-24 Published:2017-10-25 Online:2017-11-03
  • Contact: GUO Wei-chun. E-mail: guoweichun@aliyun.com

Abstract: Spine cord injury is a kind of severe central nervous system trauma causing motion and sensation dysfunction. Treatment focuses on controlling secondary injury cascade and improving regeneration which are heavily regulated by microRNAs (miRNAs). This review discussed the effect of miRNAs with different subtypes on spine cord injury, and investigated their potential roles as therapeutic agents in the personalized treatment of patients with spine cord injury.

Key words: microRNA, spine cord injury, diagnosis, treatment, prognosis, review

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