双侧颈总动脉结扎致血管性痴呆大鼠模型研究进展

doi:10.3969/j.issn.1006-9771.2018.03.012

Abstract

Abstract: Rats after permanent bilateral common carotid artery ligation would result in cerebral blood flow reduction, learning and memory dysfunction, neuronal injury and death, synaptic and dendritic injury, and neuroinflammation, etc., which reproduce the pathology and clinical symptoms of human vascular dementia, that help for further research on pathophysiology and treatment of vascular dementia.

Key words: vascular dementia, bilateral common carotid artery ligation, cognitive function, neuron, synapse, neuroinflammation, rats, review

CLC Number:

R749.1

MENG Min, LI Lin. Progress in Vascular Dementia Rat Model Induced by Bilateral Common Carotid Artery Ligation (review)[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2018, 24(3): 309-312.

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Progress in Vascular Dementia Rat Model Induced by Bilateral Common Carotid Artery Ligation (review)

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