《Chinese Journal of Rehabilitation Theory and Practice》 ›› 2018, Vol. 24 ›› Issue (4): 373-377.doi: 10.3969/j.issn.1006-9771.2018.04.001

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Application Progress of Dehydrating Agent in Acute Spinal Cord Injury (review)

ZHANG Chao1, 3, 4, LI Jian-jun1, 3, 4, YANG De-gang1, 3, 4, YANG Ming-liang1, 3, 4, DU Liang-jie1, 3, 4, ZHANG Wen-hao1, 3, 4, LIU Chang-bin1, 3, 4, LI Da-peng1, 3, 4, HU An-ming1, QIN Chuan1, 3, 4   

  1. 1. Capital Medical University School of Rehabilitation Medicine, Beijing 100068, China;
    2. a. Department of Spinal and Neural Function Reconstruction, b. Department of Neurosurgery, Beijing Bo'ai Hospital, China Rehabilitation Research Center, Beijing 100068, China;
    3. Center of Neural Injury and Repair, Beijing Institute for Brain Disorders, Beijing 100068, China;
    4.Beijing Key Laboratory of Neural Injury and Rehabilitation, Beijing 100068, China
  • Received:2017-12-18 Revised:2018-01-27 Published:2018-04-25 Online:2018-04-27
  • Contact: LI Jian-jun. E-mail: crrc100@163.com

Abstract: Acute spinal cord injury (ASCI) can be divided into primary injury and secondary injury. Spinal cord edema is important for the development of secondary injury after ASCI. Spinal cord edema can be mainly divided into cytotoxic edema and angioedema. The application of dehydrating agents in the treatment of acute spinal cord injury is obvious. This article described the application of mannitol, hypertonic saline, glycerol fructose, furosemide, human serum albumin, resveratrol and other dehydrating agents in the treatment of ASCI.

Key words: spinal cord injury, edema, dehydrating agent, review

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