Abstract: Objective To explore the effect of pulmonary rehabilitation on activities of daily living (ADL) and pulmonary function in patients with chronic schizophrenia complicated with pulmonary infection at stable stage.Methods From January, 2014 to July, 2017, 62 patients with chronic schizophrenia complicated with pulmonary infection at stable stage were randomly divided into control group (n=31) and observation group (n=31). Both groups accepted routine medication, while the observation group received pulmonary rehabilitation for two months in addition. The distance of 6-Minute Walk Test (6MWT), the modified Barthel index (MBI), modified British Medical Research Council Dyspnea Scale (mMRC), C-reactive protein (CRP), Zung Anxiety Self-Rating Scale and Zung Depression Self-Rating Scale were compared before and after training.Results The total effective rate was higher in the observation group than in the control group (χ²=5.415, P=0.020). Compared with the control group, the distance of 6MWT increased (t=5.463, P=0.008), the score of MBI increased (t=2.142, P=0.028), the score of mMRC decreased (t=3.689, P=0.013), and the level of CRP decreased (t=-2.179, P=0.031) in the observation group. The scores of Zung Anxiety Self-Rating Scale (t=5.048, P=0.009) and Zung Depression Self-Rating Scale (t=-1.388, P=0.045) both decreased.Conclusion An early implementation of pulmonary rehabilitation could improve ADL and the exercise endurance, and reduce the incidence of infection in patients with chronic schizophrenia complicated with pulmonary infection at stable stage.

Key words: chronic schizophrenia, pulmonary infection, pulmonary rehabilitation, stable stage, activities of daily living, exercise endurance