Abstract: Objective To investigate the influence of hyperbaric oxygen (HBO) on blood pressure and heart rate in adult patients with cervical spinal cord injury (SCI) and its related factors.Methods From May 2015 to October 2017, 101 cases of adult cervical spinal cord injury in our department were selected as observation group, who were divided into four subgroups (AIS A~D) respectively, according to the ASIA score. Other 101 cases of sudden hearing loss without spinal cord injury were selected as control group, who were divided into four subgroups with gender and age matched with four subgroups of the observation group, respectively. Blood pressure and heart rate were measured before the compression, at the end of the compression, 30 minutes after oxygen taken in, before the decompression and at the end of the decompression; and were compared between groups. The fluctuations of blood pressure and heart rate were correlated and regression analyzed with age, course and AISA score respectively.Results In ASI A~C, the blood pressure fluctuated obviously during the course of hyperbaric oxygen therapy in the observation group (P<0.05). There was no significant difference in blood pressure between ASI D of the observation group and their controls (P>0.05). Lower extremity motor score of ASIA was correlated with the fluctuation of blood pressure (P<0.05).Conclusion The blood pressure fluctuates in patients with cervical spinal cord injury (AIS A~C) during hyperbaric oxygen, which should be paid attention to. Lower extremity motor score of ASIA is an independent factor affecting blood pressure. The higher the lower extremity motor score, the smaller the blood pressure fluctuation.

Key words: spinal cord injury, hyperbaric oxygen therapy, blood pressure, heart rate, relevant factors