帕金森病患者的血脂水平及其相关性

doi:10.3969/j.issn.1006-9771.2019.03.019

Abstract

Abstract: Objective To investigate the relationship between serum lipids and Parkinson's disease, and its predictive value for Parkinson's disease. Methods From January, 2016 to November, 2018, 145 patients with Parkinson's disease and other 122 healthy subjects were selected. They were measured the various lipid indexes. Results Total cholesterol, low density lipoprotein cholesterol, Apolipoprotein A1 (ApoA1) and Apolipoprotein B (ApoB) were less in the patients than in the controls (t > 2.089, P < 0.05). ApoA1 was an independent protective factor from Logistic regression (OR = 0.081, P < 0.01). The most optimal cut-off threshold of ApoA1 was 1.38 mmol/L, with the sensitivity of 0.72 and the specificity of 0.68. Conclusion The lipid decreased in patients with Parkinson's disease. Low ApoA1 may be a potential independent risk factor for Parkinson's disease, which may be a predictor for it.

Key words: Parkinson's disease, serum lipids, apolipoprotein A1, correlation

CLC Number:

R742.5

YU Hong-yuan, HE Jing-hua, LIU Shuang, SUN Li-juan, YIN Yan. Relationship between Serum Lipid Levels and Parkinson's Disease[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2019, 25(3): 352-356.

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Relationship between Serum Lipid Levels and Parkinson's Disease

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