IκB激酶β在脊髓损伤后炎症反应机制中作用的研究进展

doi:10.3969/j.issn.1006-9771.2019.06.003

Abstract

Abstract: IκB kinase beta (IKKbeta) is a key kinase in nuclear factor kappa B (NF-kappaB) signaling pathway. After spinal cord injury, IKKbeta is activated, and the signal pathway of NF-kappa B is abnormally activated, which produces a large number of inflammatory factors, which has a negative impact on the recovery of spinal cord injury. This article mainly summarized the structure and function of IKKbeta and its application in inflammatory reaction after spinal cord injury, trying to find a new target for the treatment of spinal cord injury.

Key words: IκB kinase beta, spinal cord injury, inflammatory response, nuclear factor kappa B, review

CLC Number:

R651.2

TANG Rui-ling, LI Min, WANG Jun-yu, XIANG Wu, ZHANG An-ren. Advance in Role of IκB Kinase beta in Inflammatory Response Mechanism post Spinal Cord Injury (review)[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2019, 25(6): 634-637.

References

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Advance in Role of IκB Kinase beta in Inflammatory Response Mechanism post Spinal Cord Injury (review)

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