《Chinese Journal of Rehabilitation Theory and Practice》 ›› 2019, Vol. 25 ›› Issue (6): 638-643.doi: 10.3969/j.issn.1006-9771.2019.06.004

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Advance in Mechanism of Limb Spasm after Spinal Cord Injury (review)

FAN Liang-hua1, DU Liang-jie1,2   

  1. 1.Capital Medical University School of Rehabilitation Medicine, Beijing 100068, China;
    2.Department of Spinal Cord Neural Functional Reconstruction, Beijing Bo'ai Hospital, China Rehabilitation Research Center, Beijing 100068, China
  • Received:2018-11-10 Revised:2019-01-24 Online:2019-06-25
  • Contact: DU Liang-jie, E-mail: strongneck@qq.com
  • Supported by:
    Beijing Municipal Commission of Science and Technology Capital Clinical Characteristic Application Research Project (No. Z171100001017026)

Abstract: After spinal cord injury, patients often suffer from limb spasm, which affects their daily life and the progress of rehabilitation. Balance among spinal cord excitability network, presynaptic inhibition and motor neuron excitability was broken, background of motor neuron activity changed, membrane ion channels, serotonin receptors and transporter concentration changed after spinal cord injury, which promote formation and development of spasm.

Key words: spinal cord injury, spasm, pathogenesis, review

CLC Number: