节律性经颅交流电刺激对运动序列学习能力的影响

doi:10.3969/j.issn.1006-9771.2019.11.012

Abstract

Abstract: Objective To investigate the effects of transcranial alternating current stimulation (tACS) on electroencephalography (EEG) rhythm and cognitive function. Methods In December, 2017, 60 healthy young volunteers were divided into four groups equally, who accepted 20 Hz real or sham tACS on left C3 or right C4. They were asked to complete four types of finger sequence key pressing tasks (left/right hand random/regular key pressing) before and after stimulation, while the EEG signals were collected and the reaction time and accuracy were observed. EEG signals were analyzed with multiple difference analysis of event-related spectral perturbation. Results The reaction time of contralateral hand reduced after C4 real stimulation. Conclusion Right 20 Hz tACS can improve the learning of contralateral limb sequential movement.

Key words: transcranial alternating current stimulation, serial reaction time task, electroencephalography, motor learning, event-related spectral perturbation

CLC Number:

R454.1

WEI Ze, XU Min-peng, MING Dong, MU Si-yu. Effects of Transcranial Alternating Current Stimulation on Serial Reaction Time Task[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2019, 25(11): 1327-1331.

References

1 MatsuyaR, UshiyamaJ, UshibaJ. Inhibitory interneuron circuits at cortical and spinal levels are associated with individual differences in corticomuscular coherence during isometric voluntary contraction [J]. Sci Rep, 2017, 7: 44417.
2 GuerraA, PogosyanA, NowakM, et al. Phase dependency of the human primary motor cortex and cholinergic inhibition cancelation during beta tACS [J]. Cereb Cortex, 2016, 26(10): 3977-3990.
3 SchilbergL, EngelenT, Ten OeverS, et al. Phase of beta-frequency tACS over primary motor cortex modulates corticospinal excitability [J]. Cortex, 2018, 103: 142-152.
4 关龙舟,魏云,李小俚. 经颅电刺激——一项具有发展前景的脑刺激技术[J]. 中国医疗设备, 2015, 30(11): 1-5.
5 GiovannellaM, Iba?ezD, Gregori-PlaC, et al. Concurrent measurement of cerebral hemodynamics and electroencephalography during transcranial direct current stimulation [J]. Neurophotonics, 2018, 5(1): 015001.
6 耿昌. 中医药综合康复在缺血性脑卒中急性期的作用的研究[D]. 济南:山东中医药大学, 2005.
7 EdagawaK, KawasakiM. Beta phase synchronization in the frontal-temporal-cerebellar network during auditory-to-motor rhythm learning [J]. Sci Rep, 2017, 7: 42721.
8 WesselM J, ZimermanM, HummelF C. Non-invasive brain stimulation: an interventional tool for enhancing behavioral training after stroke [J]. Front Hum Neurosci, 2015, 9: 265.
9 de la SalleS, ChoueiryJ, ShahD, et al. Effects of ketamine on resting-state EEG activity and their relationship to perceptual/dissociative symptoms in healthy humans [J]. Front Pharmacol, 2016, 7: 348.
10 WesterbergC E, FlorczakS M, WeintraubS, et al. Memory improvement via slow oscillatory stimulation during sleep in older adults [J]. Neurobiol Aging, 2015, 36(9): 2577-2586.
11 JohannesV, Huster RenéJ, HerrmannC S. Increase in short-term memory capacity induced by down-regulating individual theta frequency via transcranial alternating current stimulation [J]. Front Hum Neurosci, 2015, 9: 257.
12 SchutteI, KenemansJ L, SchutterD J L G. Resting-state theta/beta EEG ratio is associated with reward-and punishment-related reversal learning [J]. Cogn Affect Behav Ne, 2017, 17(4): 754-763.
13 PollokB, BoysenA C, KrauseV. The effect of transcranial alternating current stimulation (tACS) at alpha and beta frequency on motor learning [J]. Behav Brain Res, 2015, 293: 234-240.
14 NowakM, HinsonE, van EdeF, et al. Driving human motor cortical oscillations leads to behaviorally relevant changes in local GABAA inhibition: a tACS-TMS study [J]. J Neurosci, 2017, 37(17): 4481-4492.
15 HerrmannC S, StrüberD, HelfrichR F, et al. EEG oscillations: from correlation to causality [J]. Int J Psychophysiol, 2016, 103: 12-21.
16 BauerA K R, KreutzG, HerrmannC S. Individual musical tempo preference correlates with EEG beta rhythm [J]. Psychophysiology, 2015, 52(4): 600-604.
17 VossU, HolzmannR, HobsonA, et al. Induction of self awareness in dreams through frontal low current stimulation of gamma activity [J]. Nat Neurosci, 2014, 17(6): 810-812.
18 HiranoM, KubotaS, KoizumeY, et al. Acquisition of motor memory determines the interindividual variability of learning-induced plasticity in the primary motor cortex [J]. J Appl Physiol, 2018, 125(4): 990-998.
19 Fr?hlichF. Endogenous and exogenous electric fields as modifiers of brain activity: rational design of noninvasive brain stimulation with transcranial alternating current stimulation [J]. Dialogues Clin Neuro, 2014, 16(1): 93-102.
20 SalmelaE, RenvallH, KujalaJ, et al. Evidence for genetic regulation of the human parieto‐occipital 10‐Hz rhythmic activity [J]. Eur J Neurosci, 2016, 44(3): 1963-1971.
21 FigueiredoJ, SantosC P, MorenoJ C. Automatic recognition of gait patterns in human motor disorders using machine learning: a review [J]. Med End Phys, 2018, 53: 1-12.
22 RufenerK S, ZaehleT, OechslinM S, et al. 40 Hz-Transcranial alternating current stimulation (tACS) selectively modulates speech perception [J]. Int J Psychophysiol, 2016, 101: 18-24.
23 SamahaJ, IemiL, PostleB R. Prestimulus alpha-band power biases visual discrimination confidence, but not accuracy [J]. Conscious Cogn, 2017, 54: 47-55.
24 GiordanoN, IemoloA, ManciniM, et al. Motor learning and metaplasticity in striatal neurons: relevance for Parkinson's disease [J]. Brain, 2018, 141(2): 505-520.
25 PollokB, OverhagenC L, KeitelA, et al. Transcranial direct current stimulation (tDCS) applied to the left dorsolateral premotor cortex (dPMC) interferes with rhythm reproduction [J]. Sci Rep, 2017, 7(1): 11509.
26 MeissnerS N, KrauseV, SüdmeyerM, et al. The significance of brain oscillations in motor sequence learning: Insights from Parkinson's disease [J]. Neuroimage, 2018, 20: 448-457.

[1]	CHEN Yu, GUO Feng, GUO Jianrui, DONG Tongtong, XIA Xuelian. Activation characteristics of motor cortex during mirror visual feedback based on electroencephalography [J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2023, 29(8): 967-976.
[2]	GUO Feng,HAO Ying,CHEN Yu. Brain sources characteristics during movement of residual limbs in forearm amputees based on standard low resolution brain electromagnetic tomography technology [J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2022, 28(8): 972-980.
[3]	LIU Shaowen,WEI Conghui,SHAN Xinying,ZHANG Yan. Brain functional connectivity in lower limb amputees [J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2022, 28(1): 90-94.
[4]	DU Yu-peng,LI Xiao-dong,LIU Wen-bing,LIU Xue-yun. Intensities of Transcranial Direct Current Stimulation for Dysphagia after Cerebral Infarction [J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2020, 26(5): 583-587.
[5]	AN Wen-jun, LI Jin-hua, WANG He-ping. Advance in Electroencephalographic and Imaging Studies in Depression Children and Adolescents (review) [J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2019, 25(3): 314-318.
[6]	LI Na, CUI Zhi-qin, SHI Chang-cheng, ZUO Guo-kun. Effect of Real-time Visual Trajectory Feedback on Upper Limb Movement Learning [J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2019, 25(2): 217-223.
[7]	YAN Yun, LI Qing-ping, DONG Wen-bin, JIA Wen, GUO Lin, ZHAI Xue-song, KANG Lan. Effect of Mild Hypothermia Therapy on Neonatal Bilirubin Encephalopathy: Evaluated with ¹⁸F-fluorodeoxyglucose Positron Emission Tomography/CT and Amplitude Integrated Electroencephalogram [J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2017, 23(6): 690-695.
[8]	HU Meng;LIU Xin-you;FU Xiao-hui;et al.. Application of Benadrly in Test of Drug-induced Electroencephalography of Epilepsy [J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2010, 16(6): 587-588.
[9]	WANG Lei;HE Yi;ZHENG Hu;et al. Effects of Hyperbaric Oxygen Combined with Fastigial Nucleus Stimulation on Chronic Cerebral Circulation Insufficiency with Transcranial Doppler and Electroencephalography [J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2009, 15(12): 1130-1132.

Effects of Transcranial Alternating Current Stimulation on Serial Reaction Time Task

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 9

Metrics

Comments

Recommended 0