小胶质细胞膜受体在阿尔茨海默病中的作用

doi:10.3969/j.issn.1006-9771.2020.01.011

Abstract

Abstract:

β-amyloid (Aβ) plaque deposition, neurofibrillary tangles and neuroinflammation are important pathological features of Alzheimer's disease (AD). Microglial membrane receptors, such as triggering receptor expressed on myeloid cells 2, Toll-like receptors, complement system and scavenger receptor, play a key role that mediate neuroinflammatory responses, promote Aβ clearance and signal transduction.

Key words: Alzheimer's disease, microglia, receptor, review

CLC Number:

R749.1

LIN Hua-wei,LIU Wei-lin,WANG Zhi-fu,TAO Jing,CHEN Li-dian. Roles of Microglial Membrane Receptors in Alzheimer's Disease (review)[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2020, 26(1): 62-66.

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Roles of Microglial Membrane Receptors in Alzheimer's Disease (review)

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