运动通过调控线粒体质量控制改善肌少症的研究进展

doi:10.3969/j.issn.1006-9771.2020.09.012

Abstract

Abstract:

Sarcopenia is a process in which skeletal muscle mass and strength are gradually declining, resulting a main health challenge for the old adults. Mitochondria can maintain the integrity of structure and function of skeletal muscle by improving biosynthesis, antioxidant defense, fusion/fission dynamics and mitophagy. Mitochondrial dysfunction is a important factor leading to the complex etiology of sarcopenia. Exercise can regulate mitochondrial quality control pathways by activating mitochondrial biogenesis and mitophagy to maintain optimal mitochondrial function, thereby delaying and preventing the onset and progression of sarcopenia.

Key words: sarcopenia, mitochondrial quality control, exercise intervention, mitophagy, review

WANG Cen-yi,LIANG Ji-ling,SI Yu-hao,CHEN Ning. Advance in Role of Mitochondrial Quality Control in Exercise for Sarcopenia (review)[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2020, 26(9): 1066-1070.

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Advance in Role of Mitochondrial Quality Control in Exercise for Sarcopenia (review)

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