咽部电刺激治疗脑卒中后吞咽障碍的Meta分析

doi:10.3969/j.issn.1006-9771.2020.11.006

Abstract

Abstract:

Objective To evaluate the effect of pharyngeal electrical stimulation (PES) on post-stroke dysphagia.Methods Randomized controlled trial (RCT) about pharyngeal electrical stimulation for dysphagia after stroke were searched in Coehrane Library, Embase, EBSCO, PubMed, Web of Science, CBM, VIP, CNKI and Wanfang Data until June, 2020. The literature quality was evaluated, and the data were analyzed with RevMan 5.3.Results Five RCTs were returned, including 325 patients. PES was more effective in improvement of Dysphagia Severity Rating Scale scores (SMD = -0.27, 95%CI -0.53 to -0.01, P = 0.04) and decannulation rate (RR = 4.69, 95%CI 2.02 to 10.87,P < 0.001); however, there was no significant difference in Functional Oral Intake Scale scores (SMD = 0.24, 95%CI -0.32 to 0.79, P = 0.40), Penetration-Aspiration Scale scores (MD = -0.18, 95%CI -0.74 to 0.39, P = 0.54) and length of stay (SMD = -0.16, 95%CI -0.42 to 0.11, P = 0.25) between PES and control.Conclusion Pharyngeal electrical stimulation can improve the swallowing function and enhance decannulation rate for post-stroke dysphagia, while it is uncertain for functional oral intake, risk of aspiration and length of stay.

Key words: stroke, dysphagia, pharyngeal electrical stimulation, meta analysis

CLC Number:

R743.3

XIAO Hui-fang,WANG Ran-ran,WANG De-qiang. Pharyngeal Electrical Stimulation for Post-stroke Dysphagia: A Meta-analysis[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2020, 26(11): 1280-1286.

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References 23

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研究	国家					对照组				结局指标
研究	国家	n	男/女(n)	年龄 (岁)	干预措施	n	男/女(n)	年龄 (岁)	干预措施	结局指标
Jayasekeran等(2010)^[7]	英国	16	10/6	75±2.7	PES(5 Hz,14.4 mA,10 min)	12	9/3	74±2.3	假刺激	PAS,DSRS,住院时间
Bath等 (2016)^[14]	德国	87	48/39	74.0±9.9	PES(5 Hz,14.8 mA,10 min)+常规治疗	75	46/29	74.9±12.6	假刺激+常规治疗	DSRS,PAS,住院时间
Vasant等 (2014)^[12]	英国	18	11/7	71	PES(5 Hz,75%最大耐受强度,10 min)	18	10/8	71	假刺激	PAS,DSRS,住院时间
Suntrup等 (2015)^[13]	德国	20	9/11	63.0±14.5	PES(5 Hz,10 min)	10	6/4	66.7±14.5	假刺激	拔管率,住院时间
Dziewa等 (2018)^[15]	德国	35	24/11	61.7±13.0	PES(5 Hz,10 min)	34	20/14	66.8±10.3	假刺激(5 Hz,10 min)	拔管率,DSRS,FOIS

研究	条目1	条目2	条目3	条目4	条目5	条目6	条目7	条目8	条目9	条目10	条目11	总分	等级
Jayasekeran等(2010)^[7]	1	1	1	1	0	0	1	0	0	1	1	7	中
Bath等(2016)^[14]	1	1	0	1	1	1	1	0	1	1	1	9	高
Vasant等(2014)^[12]	1	1	1	0	1	1	1	0	1	1	1	9	高
Suntrup等(2015)^[13]	1	1	0	1	0	0	0	1	0	1	1	6	中
Dziewa等(2018)^[15]	1	1	0	1	0	0	1	1	0	1	1	7	中

Pharyngeal Electrical Stimulation for Post-stroke Dysphagia: A Meta-analysis

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