《Chinese Journal of Rehabilitation Theory and Practice》 ›› 2021, Vol. 27 ›› Issue (1): 48-53.doi: 10.3969/j.issn.1006-9771.2021.01.007

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Advance in Application of Neuroimaging in Plasticity Mechanism after Stroke (review)

ZHANG Hao-jie1,2, LI Fang1,2, LI Chao-jin-zi1,2, MI Hai-xia1,2, LIU Xu1,2, BAI Chen1,2, LI Bing-jie1,2, DU Xiao-xia1,2, ZHANG Tong1,2   

  1. 1. Capital Medical University School of Rehabilitation Medicine, Beijing 100068, China
    2. Department of Neurology, Beijing Bo'ai Hospital, China Rehabilitation Research Centre, Beijing 100068, China
  • Received:2019-11-27 Revised:2020-03-30 Published:2021-01-25 Online:2021-01-27
  • Contact: ZHANG Tong, E-mail: tom611@126.com
  • Supported by:
    China Rehabilitation Research Centre Project (No. 2018ZX-10) and National Special Fund of Basic Research of Public Benefits for Institutes at Central Governmental Level (No. 2018CZ-2)

Abstract: Neuroimaging technique is a kind of significant means to explore the mechanism of cerebral plasticity after stroke. Diffusion tensor imaging can be used to describe the structure of white matter fiber bundles and evaluate the degree of damage, but it cannot reflect the functional connections between different brain regions. Task-state functional magnetic resonance (fMRI) can detect the activation of corresponding brain regions caused by specific tasks, but the test design is complex and demanding for subjects. Resting-state fMRI can analyze complex brain networks and reflect functional connections in different brain regions, but the method of data analysis is complex. Functional near-infrared spectroscopy (fNIRS) is another non-invasive method to reflect the functional activation of brain regions, in which temporal resolution is better than fMRI, but the spatial resolution is slightly lower. The combination of multiple detection methods may be an important research direction in the future.

Key words: stroke, rehabilitation, plasticity, neuroimaging, magnetic resonance imaging, near-infrared spectroscopy, review

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