《Chinese Journal of Rehabilitation Theory and Practice》 ›› 2021, Vol. 27 ›› Issue (1): 67-70.doi: 10.3969/j.issn.1006-9771.2021.01.010

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Roles of Notch Signaling Pathway in Acupuncture for Ischemic Stroke (review)

WANG Na-na, DU Xiao-zheng, HE Wen-jie, ZHANG Xin-yu, ZHENG Xin, LI Meng-xin   

  1. Department of Acupuncture and Massage, Gansu University of Chinese Medicine, Lanzhou, Gansu 730000, China
  • Received:2019-07-31 Revised:2019-09-16 Published:2021-01-25 Online:2021-01-27
  • Contact: DU Xiao-zheng, E-mail: lz-duxiaozheng@163.com
  • Supported by:
    Gansu Administration of Traditional Chinese Medicine Research Project (No. GZK-2017-10) and Gansu Science and Technology Department Innovation Base and Talent Program (No. 18JR3RA196)

Abstract: Notch signaling pathway is a highly conserved signaling pathway in evolution, which would be activated to play a role in apoptosis, angiogenesis, neurogenesis, immune inflammation and others after ischemia. After acupuncture for ischemic stroke, the expression of Notch signaling pathways related factors increase, which may play a role in neurogenesis, ischemic tolerance, apoptosis, angiogenesis, and so on.

Key words: ischemic stroke, acupuncture, Notch signaling pathway, review

CLC Number: