功能性近红外光谱技术在利手、非利手主动抓握-释放任务下脑区激活研究中的应用

doi:10.3969/j.issn.1006-9771.2021.09.010

Abstract

Abstract:

Objective To apply functional near-infrared spectroscopy (fNIRS) to analyze brain activity pattern of bilateral sensorimotor cortex (SMC) and premotor cortex (PMC) during complex dominant and non-dominant hand movement in healthy subjects.Methods From August to December, 2019, 15 right-handed healthy residents were recruited. The block designed grip-release task was used in the subjects, and detected oxyhemoglobin and deoxyhemoglobin concentration with fNIRS to analyze the activation of bilateral SMC, PMC and prefontal cortex in term of activation channels and intensity.Results For the oxyhemoglobin concentration, the number of activated channels was the same in both hemispheres during right (dominant) hand movement, and the activation of left SMC was stronger (P < 0.05); however, more channels were activated in the right hemisphere during left (non-dominant) hand movement, and the activation of right SMC was stronger (P < 0.05). For the deoxyhemoglobin concentration, more channels were activated in the contralateral hemisphere during either dominant or non-dominant hand movement, and the activation of left SMC, Channel 12 (left PMC) and Channel 26 (right PMC) were stronger during right (dominant) hand movement (P < 0.05).Conclusion It is feasible to use fNIRS to study the activation of hand movement related brain regions during complex movement of dominant and non-dominant hand, especially with the results of oxyhemoglobin concentration.

Key words: functional near-infrared spectroscopy, upper extremity, motor function, sensorimotor cortex, premotor cortex

LI Chao-jin-zi,HUANG Fu-biao,DU Xiao-xia,ZHANG Hao-jie,ZHANG Tong. Application of Functional Near-infrared Spectroscopy in Brain Area Activation Research: Dominant and Non-dominant Hand under Active Grasp-release Task[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2021, 27(9): 1066-1071.

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通道	脑区	左手任务	右手任务	P值
4	左SMC	2.230	3.340	0.038
5		2.520	4.860	0.004
8		2.480	4.420	0.002
9		2.640	5.000	0.003
平均		2.468	4.405	0.002
12	左PMC	2.440	4.160	0.026
13	左PMC	2.410	3.450	0.014
平均		2.425	3.805	0.160
29	右SMC	2.790	2.220	0.046
32		3.201	2.220	0.013
36		2.910	2.120	0.023
平均		2.967	2.187	0.003

通道	脑区	左手任务	右手任务	P值
1	左侧SMC	0.423	0.972	0.009
4		0.588	0.988	0.045
5		0.635	1.770	0.006
8		0.462	1.290	0.005
9		0.752	1.690	0.004
平均		0.572	1.342	0.003
12	左PMC	2.440	4.160	0.026
26	右PMC	2.410	3.450	0.014
32	右SMC	1.130	5.430	0.004
36		1.050	0.425	0.003
48		0.282	-0.394	0.025
平均		0.821	1.820	0.191

Application of Functional Near-infrared Spectroscopy in Brain Area Activation Research: Dominant and Non-dominant Hand under Active Grasp-release Task

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