经颅直流电刺激调节迷走神经兴奋性对脑卒中后吞咽障碍的效果

doi:10.3969/j.issn.1006-9771.2021.09.012

Abstract

Abstract:

Objective To study the effect of transcranial direct current stimulation (tDCS) regulating excitability of the vagus nerve on dysphagia after stroke.Methods From September, 2020 to February, 2021, 28 patients with dysphagia after stroke were randomly divided into control group (n = 14) and tDCS group (n = 14). Both groups accepted swallowing function training, and tDCS group received anodal tDCS over vagus nerve, while the control group received sham tDCS. They were assessed with modified Mann Assessment of Swallowing Ability (MMASA) and Australian Therapy Outcome Measures (AusTOMs)-swallowing scale before and after treatment.Results The scores of MMASA (|t| > 5.593, P < 0.001) and AusTOMs swallowing scale (|Z| > 2.121, P < 0.05) increased in both groups after treatment, and were higher in tDCS group than in the control group (|t| = 2.439, |Z| = 2.079, P < 0.05).Conclusion Anodal tDCS over vagus nerve may further release dysphagia after stroke.

Key words: stroke, dysphagia, transcranial direct current stimulation, vagus nerve

CHEN Jia-jun,WU Deng-chong,SHAO Xiang-zhi,PU Xin-yu,MAO Yan-wu,CHEN Bing. Effects of Transcranial Direct Current Stimulation over Vagus Nerve on Dysphagia after Stroke[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2021, 27(9): 1078-1081.

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组别	n	性别(男/女, n)	年龄(岁)	病程(d)	病变性质(出血/梗死, n)
对照组	14	12/2	63±12.1	98±9.1	2/12
tDCS组	14	13/1	65±9.5	102±15.5	0/14
t值			0.610	0.635
P值		1.000^a	0.553	0.536	0.481^a

组别	n	治疗前	治疗后	t值	P值
对照组	14	65.5±8.8	70.9±7.8	-5.593	< 0.001
tDCS组	14	66.3±6.7	76.8±4.5	-6.623	< 0.001
t值		0.267	2.439
P值		0.792	0.022

组别	n	治疗前	治疗后	Z值	P值
对照组	14	1.64±1.01	2.07±0.83	-2.121	0.034
tDCS组	14	1.79±1.25	3.07±1.21	-3.145	0.002
Z值		-0.048	-2.079
P值		0.962	0.038

Effects of Transcranial Direct Current Stimulation over Vagus Nerve on Dysphagia after Stroke

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