针刺治疗孤独症谱系障碍儿童便秘的效果

doi:10.3969/j.issn.1006-9771.2021.10.012

Abstract

Abstract:

Objective To observe the effect of acupuncture on constipation in children with autism spectrum disorder (ASD).Methods From January, 2019 to November, 2020, 50 ASD children with constipation from Rehabilitation Center of the Second Affiliated Hospital of Heilongjiang University of Chinese Medicine were admitted and randomly divided into acupuncture-rehabilitation group (n = 25) and medicine-rehabilitation group (n = 25). For constipation, the acupuncture-rehabilitation group used scalp acupuncture, body acupuncture combined with rehabilitation; the medicine-rehabilitation group took probiotics orally combined with rehabilitation. Both groups received conventional rehabilitation for constipation and the core symptoms. Constipation was treated for eight weeks, and ASD symptoms was treated for twelve weeks. After eight weeks and twelve weeks, the efficacy of constipation and the scores of main symptoms of constipation were compared, and they were also evaluated with Autism Child Behavior Scale (ABC) and Autism Treatment Evaluation Scale (ATEC).Results Before treatment, there was no significant difference in the main symptoms of constipation, nor the scores of ABC and ATEC between two groups (P > 0.05). Eight weeks after treatment, the main symptoms of constipation significantly improved (t > 5.473, P < 0.001); twelve weeks after treatment, the efficacy of constipation and the main symptoms of constipation were better in the acupuncture-rehabilitation group than in the medicine-rehabilitation group (Z = 2.848, t = -2.139, P < 0.05). Eight weeks after treatment, the scores of ABC and ATEC significantly decreased (t > 7.139, P < 0.001), and there was no significant difference between two groups (P > 0.05); the score of behavior of ATEC significantly decreased in the acupuncture-rehabilitation group (t = 3.849, P < 0.01), and was lower than that of the medicine-rehabilitation group (t = -2.643, P < 0.05), and no significant difference in other items was found between two groups (P > 0.05); twelve weeks after treatment, the scores of ABC and ATEC were lower in the acupuncture-rehabilitation group than in the medicine-rehabilitation group (|t| > 2.156, P < 0.05).Conclusion Acupuncture-rehabilitation can improve the longer-lasting effect of constipation, and also improve the core symptoms of ASD, which is superior to medicine-rehabilitation.

Key words: autism spectrum disorder, acupuncture, probiotics, constipation

CLC Number:

R749.94

ZHANG Chun-yan,WANG Yan,LI Hong-yu,ZHUANG Ya-nan,ZHU Shu-wei,XU Dan-shuang,ZHANG Xue-wei,CHEN Hui-jie. Effect of Acupuncture on Constipation in Children with Autism Spectrum Disorder[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2021, 27(10): 1211-1217.

Figures/Tables 8

References 30

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组别	n	性别(n)		年龄(岁)	ASD病程(年)	ASD病情(n)
组别	n	男	女	年龄(岁)	ASD病程(年)	轻中度	重度
针康组	24	19	5	4.06±1.04	1.23±0.63	19	5
药康组	23	19	4	4.13±1.03	1.22±0.61	19	4
χ²/t值		0.764		0.213	0.026	0.764
P值		0.090		0.832	0.980	0.090

主症	正常(0分)	轻度(2分)	中度(4分)	重度(6分)
大便性状	4型、5型	3型或先3型后4型、5型	2型或先2型后4型、5型	1型
排便情况	正常	排便费力	排便努挣方出	排便努挣难出
排便频次	1~2 d 1次	3 d 1次	4~5 d 1次	每周< 1次

组别	n	治愈	显效	有效	无效
针康组	24	7	10	5	2
药康组	23	3	5	8	7

组别	n	治愈	显效	有效	无效
针康组	24	6	7	8	3
药康组	23	1	3	10	9

组别	n	治疗前	治疗8周	治疗12周	t值^a	P值^a	t值^b	P值^b
针康组	24	11.76±3.05	8.75±2.97	9.05±3.15	7.901	< 0.001	8.782	< 0.001
药康组	23	12.41±3.28	10.75±3.22	11.15±2.77	5.473	< 0.001	1.187	0.253
t值		-0.697	-0.502	-2.319
P值		0.491	0.048	0.026

Effect of Acupuncture on Constipation in Children with Autism Spectrum Disorder

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组别	n	治疗前	治疗8周	治疗12周	t值^a	P值^a	t值^b	P值^b
针康组	24	82.45±9.00	77.55±8.89	67.95±8.91	11.640	< 0.001	13.976	< 0.001
药康组	23	83.95±8.34	78.25±9.25	74.21±9.42	7.139	< 0.001	13.566	< 0.001
t值		-0.546	-0.244	-2.156
P值		0.588	0.809	0.038

组别	n	治疗前	治疗8周	治疗12周	t值	P值	t值^b	P值^b
针康组	24	98.16±5.99	88.47±5.57	79.86±5.77	63.364	< 0.001	82.758	< 0.001
药康组	23	98.48±6.08	90.39±5.89	86.56±5.69	58.032	< 0.001	30.774	< 0.001
t值		-0.240	-0.982	-3.960
P值		0.981	0.331	< 0.001

组别	n		语言	社交	认知	行为
针康组	24	治疗前	15.71±3.32	23.80±3.54	13.65±1.30	33.21±4.13
		治疗8周	12.74±3.35	19.73±3.13	11.55±1.61	28.95±3.51
		治疗12周	10.12±2.31	17.25±2.79	10.15±1.66	26.61±3.58
药康组	23	治疗前	16.05±3.33	23.75±3.74	13.55±1.46	33.42±3.69
		治疗8周	13.15±3.43	21.84±3.65	12.30±1.63	31.85±3.31
		治疗12周	12.55±2.78	19.85±3.73	11.51±1.76	29.42±3.47
t值^a			2.972	4.040	2.748	3.849
P值^a			< 0.001	0.001	0.013	0.001
t值^b			13.958	7.050	6.281	30.252
P值^b			< 0.001	< 0.001	< 0.001	< 0.001
t值^c			17.105	3.368	3.651	15.158
P值^c			< 0.001	0.003	0.002	< 0.001
t值^d			4.543	6.324	5.454	4.108
P值^d			< 0.001	< 0.001	< 0.001	< 0.001
t值^e			-0.422	-1.951	-1.473	-2.643
P值^e			0.681	0.063	0.151	0.012
t值^f			-3.028	-2.496	-2.492	-2.508
P值^f			0.004	0.017	0.017	0.017

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