下肢截肢患者的脑功能连接

doi:10.3969/j.issn.1006-9771.2022.01.013

Abstract

Abstract:

Objective To investigate the changes of functional brain connectivity over multiple frequency bands in resting-state electroencephalography (EEG) for lower limb amputation patients. Methods Resting-state EEG was collected from 18 lower limb amputees and 22 healthy controls from November, 2020 to June, 2021. Functional connectivity matrix was constructed with phase-locked values (PLV), and compared between groups. Results The functional connectivity was weaker in the amputees than in the controls on α band (t = 3.433, P = 0.001) and β band (t = 3.806, P = 0.001), and there was no significant difference on δ band (t = 1.429, P = 0.161) and θ band (t = 1.211, P = 0.233). Conclusion EEG functional connectivity weakens in lower limb amputees in on the α and β band, which results in neuroplasticity of multiple brain regions, not only for limb-respond cortex, but also for frontal, temporal and occipital cortices.

Key words: lower limb, amputation, resting-state electroencephalography, functional connectivity, phase-locked values

CLC Number:

R687.5

LIU Shaowen,WEI Conghui,SHAN Xinying,ZHANG Yan. Brain functional connectivity in lower limb amputees[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2022, 28(1): 90-94.

Figures/Tables 5

References 29

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患者	性别	年龄/岁	截肢部位	病程/月	病因
1	女	57	小腿	8	交通事故
2	男	46	大腿	4	交通事故
3	男	41	小腿	7	交通事故
4	男	49	小腿	24	交通事故
5	男	49	大腿	14	交通事故
6	男	53	大腿	5	烧伤
7	男	33	大腿	6	交通事故
8	男	52	小腿	2	感染
9	女	66	大腿	8	交通事故
10	男	35	小腿	2	感染
11	男	46	小腿	19	交通事故
12	男	32	小腿	2	交通事故
13	男	34	小腿	19	电击伤
14	男	57	小腿	8	感染
15	男	62	大腿	13	交通事故
16	男	45	大腿	17	交通事故
17	男	44	大腿	20	肿瘤
18	男	50	小腿	5	交通事故

Brain functional connectivity in lower limb amputees

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组别	n	δ	θ	α	β
对照组	22	0.70±0.02	0.56±0.02	0.51±0.03	0.46±0.03
患者组	18	0.70±0.02	0.55±0.02	0.47±0.03	0.42±0.04
t值		1.429	1.211	3.433	3.806
P值		0.161	0.233	0.001	0.001

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