《Chinese Journal of Rehabilitation Theory and Practice》 ›› 2022, Vol. 28 ›› Issue (4): 399-406.doi: 10.3969/j.issn.1006-9771.2022.04.005

Previous Articles     Next Articles

Visualized analysis of researches on denervated muscle atrophy in the past five years

ZHANG Shiwen1,ZHI Jincao1,HUANG Meiling1,PEI Fei2,WANG Yan2()   

  1. 1. Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang 150040, China
    2. Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang 150001, China
  • Received:2021-12-22 Revised:2022-02-14 Published:2022-04-25 Online:2022-05-05
  • Contact: WANG Yan E-mail:swallow-1113@163.com
  • Supported by:
    National Nature Science Foundation of China (General)(81973926);Nature Science Foundation of Heilongjiang Province(LH2021H090);Heilongjiang University of Chinese Medicine "Outstanding Innovative Talents Support Program" Research Project(2018RCL10)

Abstract:

Objective To perform a visualized analysis of the current status, hotspots and frontiers of research on denervated muscle atrophy in the past five years.Methods The Web of Science core database was used to retrieve relevant documents in the field of denervated muscle atrophy, and visualized analysis was performed on CiteSpace 5.8.R3 in terms of annual number of published papers, frequency of citations, countries, institutions, authors, keywords and references.Results A total of 516 articles were retrieved from 2017 to 2021. The annual number of published papers was on the rise, and the number of citations was increasing year by year. The United States, Canada and England were high-influence countries, the University of Padua in Italy was the leading institution. The author SUN Hualin published the most articles. The authors Bodine S C and Sandri M were the main influencers. Physiological and pathological mechanisms based on cytology, molecular biology and tissue morphology, as well as prevention and treatment measures based on physical factor therapy, drugs and exercise were the research hotspots in this field. It might be coming that taking reactive oxygen species as the target and looking for multi-targeted proteolytic system drugs as the goal for prevention and treatment.Conclusion This visualized analysis has comprehensively summarized the trends and development of denervated muscle atrophy research, and identified the potential research frontiers and hot directions in the near future.

Key words: denervation, muscle atrophy, CiteSpace, visualized analysis