头颈部鳞状细胞癌术后早期吞咽障碍的临床相关因素

doi:10.3969/j.issn.1006-9771.2022.09.010

Abstract

Abstract:

Objective To explore factors related to dysphagia early after surgery for head-and-neck squamous cell carcinoma (HNSCC).
Methods A total of 80 HNSCC inpatients in Department of Oral and Maxillofacial Surgery, the Frist Affiliated Hospital of Chongqing Medical University, from October, 2019 to April, 2021, were reviewed swallowing function with Kubota water drinking test, Functional Oral Intake Scale (FOIs) and M.D. Anderson Dysphagia Inventory (MDADI), two weeks after radical surgery for the first time; while the related data were collected and analyzed.
Results The incidence of early post-operative dysphagia was 91.25%. The T stages of the tumor, the location of the primary tumor, simultaneous flap repairment and neck dissection were the factors related to dysphagia (P < 0.05), and T stages of the tumor was the independent factor (B = -5.092, t = -6.770, P < 0.001).
Conclusion It's necessary to evaluate the swallowing function of HNSCC patients after surgery, especially for those in worse stages, for early intervention.

Key words: head-and-neck squamous cell carcinoma, post-operation, dysphagia

CLC Number:

R739.8

CHENG Wei,XUE Lingli,DONG Linsheng,LI Yadong. Factors related to dysphagia early after surgery for head-and-neck squamous cell carcinoma[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2022, 28(9): 1074-1078.

Figures/Tables 3

References 32

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变量	n	MDADI	t/r/H值	P值
性别			-0.490^a	0.620
男	58	66.64±1.02
女	22	67.64±1.85
年龄	80	66.91±7.97	0.137^b	0.890
肿瘤部位			27.591^c	< 0.001
颊部	12	73.58±6.09
舌部	30	63.67±5.76
口底	16	69.06±8.50
腭部	4	62.75±1.71
牙龈	12	71.50±8.20
口咽部	6	57.66±3.20
肿瘤的T分期			32.560^c	< 0.001
T1	12	77.75±1.89
T2	20	69.10±1.25
T3	36	64.53±0.87
T4	12	59.58±2.21
皮瓣修复			4.720^a	0.001
是	32	62.34±6.43
否	48	69.95±7.46
同期颈淋巴结清扫			2.410^a	0.020
是	50	65.30±7.17
否	30	69.60±8.60

自变量	赋值
肿瘤的位置	颊部 = 1,舌部 = 2,口底 = 3,腭部 = 4,牙龈 = 5,口咽 = 6
肿瘤的T分期	T1 = 1,T2 = 2,T3 = 3,T4 = 4
同期皮瓣转移修复	是 = 1,否 = 0
同期行颈淋巴清扫术	是 = 1,否 = 0

变量	B	SE	β	95%CI	t值	P值
肿瘤的位置	-0.192	0.458	-0.037	-1.104~0.720	-0.420	0.676
肿瘤的T分期	-5.092	0.843	-0.590	-6.770~-3.411	-6.037	< 0.001
T1
T2	-8.605	2.159	-0.473	-12.951~-4.349	-4.006	< 0.001
T3	-13.220	1.971	-0.831	-17.148~-9.296	-6.707	< 0.001
T4	-18.170	2.414	-0.820	-22.975~-13.358	-7.525	< 0.001
同期行颈淋巴清扫术	-1.340	1.526	-0.082	-4.379~1.700	-0.878	0.383
同期皮瓣转移修复	-1.919	1.761	-0.119	-5.427~1.590	-1.089	0.280

Factors related to dysphagia early after surgery for head-and-neck squamous cell carcinoma

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